Uveitis in Childhood: An Italian Clinical and Epidemiological Study
Uveitis in Childhood: An Italian Clinical and Epidemiological Study
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DOI：
10.1080/09273940802702561
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发表时间：
2009-01-01
影响因子：
3.3
通讯作者：
Pezzi, Paolo Pivetti
中科院分区：
文献类型：
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作者：
Paroli, Maria Pia;Spinucci, Giovanni;Pezzi, Paolo Pivetti
目的：调查儿童葡萄膜炎的人口统计学、病因、特征和视力结果。方法：回顾性队列研究，包括257例年龄小于16岁的患者。结果：葡萄膜炎发病的平均年龄为8.54 ± 3.98岁; 54.5%的患者为女孩。前葡萄膜炎占47.8%，中葡萄膜炎占19.4%，后葡萄膜炎占24.9%，全葡萄膜炎占7.8%。双眼受累占67.8%。感染性葡萄膜炎占所有病例的31%。严重视力丧失的原因是白内障、黄斑瘢痕、黄斑水肿/黄斑病变和继发性青光眼。随访时，79.3%的患眼视力保持在20/32和20/20之间。结论：葡萄膜炎是罕见的儿童比成人。前葡萄膜炎患者构成了最大的一组。后葡萄膜炎在儿科人群中的发病率比几十年前低。由于早期诊断和正确治疗，儿童葡萄膜炎的视力预后正在改善。
Purpose: To investigate demographics, causes, features, and visual outcomes of pediatric uveitis. Methods: Retrospective cohort study including 257 patients younger than 16 years. Results: Mean age at onset of uveitis was 8.54 +/- 3.98 years; 54.5% of the patients were girls. Anterior uveitis occurred in 47.8%, intermediate in 19.4%, posterior in 24.9%, panuveitis in 7.8%. Ocular involvement was bilateral in 67.8%. Infectious uveitis represented 31% of all cases. Causes of severe visual loss were cataract, macular scars, macular edema/maculopathy, and secondary glaucoma. At follow-up 79.3% of eyes maintained a visual acuity between 20/32 and 20/20. Conclusions: Uveitis is rarer in children than in adults. Patients with anterior uveitis comprised the largest group. Posterior uveitis in the pediatric population has a lower incidence than some decades ago. Visual prognosis of pediatric uveitis is improving, owing to an earlier diagnosis and a correct treatment.