AN ANTIBODY THAT INHIBITS IN VITRO BONE MARROW PROLIFERATION IN A PATIENT WITH SYSTEMIC LUPUS ERYTHEMATOSUS AND APLASTIC ANEMIA
AN ANTIBODY THAT INHIBITS IN VITRO BONE MARROW PROLIFERATION IN A PATIENT WITH SYSTEMIC LUPUS ERYTHEMATOSUS AND APLASTIC ANEMIA
复制标题
一种抑制系统性红斑狼疮和再生障碍性贫血患者体外骨髓增殖的抗体
DOI：
10.1002/j.2326-5205.1989.tb00022.x
复制
发表时间：
1989
影响因子：
13.3
通讯作者：
G. V. Ball
中科院分区：
文献类型：
--
作者：
F. Amos Bailey;Michael Lilly;L. Bertoli;G. V. Ball
在系统性红斑狼疮和再生障碍性贫血患者的血清中检测到一种在体外抑制骨髓增殖的非补体依赖抗体。患者经糖皮质激素和血浆置换治疗后，再生障碍性贫血痊愈。在这次恢复后，再也检测不到抗体。此病例表明，系统性红斑狼疮的一种罕见但潜在致命的并发症是由于自身抗体引起的再生障碍性贫血。实验结果表明了类似病例的一种机制和治疗方法。
A non–complement‐dependent antibody that inhibits bone marrow proliferation in vitro was detected in the serum of a patient with systemic lupus erythematosus and aplastic anemia. The patient recovered from the aplastic anemia following treatment with corticosteroids and plasmapheresis. The antibody could no longer be detected after this recovery. This case demonstrates that a rare, but potentially lethal, complication of systemic lupus erythematosus is aplastic anemia due to an autoantibody. Results of the experiments suggest a mechanism for, and treatment of, similar cases.
人黑色素瘤细胞系产生粒细胞集落刺激因子。
影响因子：
2.6
作者：
Lilly,MB;Devlin,PE;Devlin,JJ;Rado,TA
通讯作者：
Rado,TA