A host-guest system based on collagen-like triple-helix hybridization
A host-guest system based on collagen-like triple-helix hybridization
复制标题
DOI：
10.1039/c7cc03055j
复制
发表时间：
2017-06-28
影响因子：
4.9
通讯作者：
Hamachi, I.
中科院分区：
文献类型：
--
作者：
Delsuc, N.;Uchinomiya, S.;Hamachi, I.
受镊子受体的启发，我们采用了一种新的策略来开发一种新的主客体体系。与胶原蛋白样三螺旋的杂交是以高亲和力和选择性发生的识别的驱动力。已经筛选了几种系统以找到最佳的主客体对，并且这种策略可以用于标签融合蛋白识别。
A strategy inspired by tweezer receptors has been employed to develop a new host-guest system. The hybridization into a collagen-like triple helix is the driving force for the recognition that occurs with high affinity and selectivity. Several systems have been screened to find the best host-guest pair and this strategy may be implemented for tag fused protein recognition.