Risk factors for preterm birth in Korea - A multicenter prospective study
Risk factors for preterm birth in Korea - A multicenter prospective study
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DOI：
10.1159/000087207
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发表时间：
2005-01-01
影响因子：
2.1
通讯作者：
Ha, EH
中科院分区：
文献类型：
--
作者：
Kim, YJ;Lee, BE;Ha, EH
早产是新生儿发病率和死亡率的主要决定因素，仍然是产科最严重的问题之一。本研究的目的是调查韩国孕妇早产的危险因素。采用前瞻性研究设计，在5个中心对2,645名妊娠20 - 42周的妇女进行了评价。患者人群仅限于单胎妊娠。对人口统计学因素、社会经济状况、既往和当前病史、当前妊娠并发症、药物和酒精滥用进行评估，并进行单变量和多变量logistic回归分析。在未经产的妇女中，显示与早产显著相关的因素如下：怀孕期间阴道出血（OR 2.6，CI 1.7 - 4.2）和平均收入低于1，000美元（OR 5.1，CI 1.9 - 13.5）。在经产妇女中显示与早产显著相关的因素如下：自然流产史（OR 2.4，CI 1.1 - 5.2）和早产史（OR 3.5，CI 1.02 - 11.8）。总之，怀孕期间阴道出血、平均收入低于1,000美元、既往自然流产和早产与早产呈正相关。版权所有（C）2005 S. Karger AG，巴塞尔。
Preterm birth is a major determinant of neonatal morbidity and mortality and remains one of the most serious problems in obstetrics. The aim of this study was to investigate the risk factors for preterm birth in Korean pregnant women. A total of 2,645 women were evaluated between 20 and 42 weeks' gestation at 5 centers using a prospective study design. The patient population is limited to singleton gestations. Demographic factors, socioeconomic statuses, previous and current medical histories, complications of current gestation, and drug and alcohol abuse were evaluated, and univariate and multivariate logistic regression analyses performed. Among nulliparous women, the factors that showed a significant association with preterm delivery were as follows; vaginal bleeding during pregnancy ( OR 2.6, CI 1.7 - 4.2), and below USD 1,000 average income ( OR 5.1, CI 1.9 - 13.5). The factors that showed a significant association with preterm delivery among multiparous women were as follows; a history of spontaneous abortion ( OR 2.4, CI 1.1 - 5.2), and a history of preterm delivery ( OR 3.5, CI 1.02 - 11.8). In conclusion, vaginal bleeding during pregnancy, below USD 1,000 of average income, prior spontaneous abortion, and prior preterm delivery, were positively associated with preterm birth. Copyright (C) 2005 S. Karger AG, Basel.