Synapse formation is related to the onset of neuron-specific enolase immunoreactivity in the avian auditory and vestibular systems.
Synapse formation is related to the onset of neuron-specific enolase immunoreactivity in the avian auditory and vestibular systems.
复制标题
突触形成与鸟类听觉和前庭系统中神经元特异性烯醇化酶免疫反应性的发生有关。
DOI：
10.1159/000112689
复制
发表时间：
1982
影响因子：
2.9
通讯作者：
Morest,DK
中科院分区：
文献类型：
--
作者：
Whitehead,MC;Marangos,PJ;Connolly,SM;Morest,DK
神经元特异性烯醇化酶（NSE）是糖酵解酶烯醇化酶的一种独特形式，在大脑中，它严格定位于分化的神经元和神经内分泌细胞中。在这份报告中，证据表明，NSE是第一次看到的发育中的小鸡听觉和前庭神经元的细胞体后不久，当他们第一次形成未成熟的突触。随后，免疫反应性NSE增加并扩散到短暂出现的结构，参与成熟突触排列的形态发生。这些数据将突触发生与特定神经元酶的分化相关联。
Neuron-specific enolase (NSE) is a unique form of the glycolytic enzyme, enolase, which, in the brain, is strictly localized in differentiated neurons and neuroendocrine cells. In this report evidence is presented that NSE is first seen in the cell bodies of developing chick auditory and vestibular neurons shortly after the time when they first form immature synapses. Subsequently, immunoreactive NSE increases and spreads into transiently appearing structures which participate in the morphogenesis of mature synaptic arrangements. These data correlate synaptogenesis with the differentiation of a specific neuronal enzyme.