A Log-linearized Peripheral Arterial Viscoelastic Index and Its Application to Endoscopic Thoracic Sympathectomy
A Log-linearized Peripheral Arterial Viscoelastic Index and Its Application to Endoscopic Thoracic Sympathectomy
复制标题
对数线性化外周动脉粘弹性指数及其在内镜胸交感神经切除术中的应用
DOI：
10.9746/sicetr.48.731
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
T. Tsuji
中科院分区：
文献类型：
--
作者：
H. Hirano;T. Horiuchi;H. Hirano;Y. Kurita;T. Ukawa;R. Nakamura;N. Saeki;M. Yoshizumi;M. Kawamoto;T. Tsuji
本文提出了一种利用生物信号（例如心电图、动脉压和脉搏血氧体积图）监测外周血管状况的新技术。二阶对数线性化模型（称为对数线性化外周动脉粘弹性模型）用于描述血压波形与透照体积描记波形之间的非线性粘弹性关系。该指数能够估计交感神经活动引起的外周动脉壁硬度的变化，然后通过在手臂位置测试和内镜胸交感神经切除术（ETS）期间监测外周血管状况来讨论该方法的有效性。作为手臂位置测试的结果，刚度与手臂位置无关（上：4.0 [%]，下：5.5 [%]）。然后，作为 ETS 的结果，在 ETS 手术之前和期间 (p < 0.01) 以及 ETS 手术期间和之后 (p < 0.01) 之间，刚度变化显着变化。上述实验结果清楚地表明，所提出的方法可以评估 ETS 期间交感神经活动的变化。
This paper proposes a novel technique to monitor peripheral vascular conditions by using biological signals, such as electrocardiogram, arterial pressure, and pulse oximetric plethysmogram. A second-order log-linearized model (called the log-linearized peripheral arterial viscoelastic model) is used to describe the nonlinear viscoelastic relationship between the blood pressure waveform and the transillumination plethysmographic waveform. The proposed index is able to estimate the changes of stiffness of peripheral arterial wall induced by sympathetic nervous activity, and the validity of the proposed method is then discussed by monitoring peripheral vascular conditions during arm position tests and during endoscopic thoracic sympathectomies (ETSs). As results of the arm position tests, the stiffness was arm position-independent (Up: 4.0 [%], Down: 5.5 [%]). Then, as results of the ETSs, the variation of the stiffness was significantly changed between before and during the ETS procedure (p < 0.01), and between during and after the ETS procedure (p < 0.01). The above experimental results clearly show that the proposed method can assess changes in the sympathetic nervous activity during ETSs.
影响因子：
56.9
作者：
AKSELROD, S;GORDON, D;COHEN, RJ
通讯作者：
COHEN, RJ