A novel and efficient synthesis of alkyl thiocyanates from alkyl halides in water using phase transfer catalysts
A novel and efficient synthesis of alkyl thiocyanates from alkyl halides in water using phase transfer catalysts
复制标题
DOI：
10.1016/j.cclet.2010.11.025
复制
发表时间：
2011-06
影响因子：
9.1
通讯作者：
M. Gorjizadeh;S. Sayyahi
中科院分区：
文献类型：
--
作者：
M. Gorjizadeh;S. Sayyahi
合成了1，4-双（三苯基膦）-2-丁烯二氯化物（BTPBDC）和1，4-双（三苯基膦）-2-丁烯二硫氰酸盐（BTPBDT），并将其用作相转移催化剂。在温和的反应条件下，卤代烷在水中可有效地转化为相应的硫氰酸烷基酯。没有观察到作为反应副产物的异硫氰酸酯形成的证据。
1,4-Bis(triphenylphosphonium)-2-butene dichloride (BTPBDC) and 1,4-bis(triphenyl phosphonium)-2-butene dithiocyanate (BTPBDT) were prepared and used as phase-transfer catalysts. Alkyl halides were converted efficiently to the corresponding alkyl thiocyanates under mild reaction conditions in water. No evidence for the formation of isothiocyanates as by-product of the reaction was observed.