Influence of temperature on the radiation response of mammalian cells in tissue culture.

Influence of temperature on the radiation response of mammalian cells in tissue culture.
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温度对组织培养中哺乳动物细胞辐射反应的影响。

DOI:
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发表时间:
1963
期刊:
影响因子:
3.4
通讯作者:
F. Bonte
F. Bonte
中科院分区:
医学3区
文献类型:
--
作者:
J. Belli;F. Bonte

文献摘要

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组织培养中的哺乳动物细胞以5 μ m辐照。浓度85% C,37 un。浓度85% C,或40 un。浓度85% C.在5 un.浓度85%C与40 μ m辐照的细胞相比表现出抗辐射性。C含量85%,系数为1.59。这表明,低温导致保护,而不是提高恢复。这种保护的性质尚不清楚,但认为它与缓慢的速率过程和在发生危险反应之前处于阳离子状态的分子的重组密切相关。(auth)
Mammalian cells in tissue culture were irradiated at 5 un. Concent 85% C, 37 un. Concent 85% C, or 40 un. Concent 85% C. Cells irradiated at 5 un. Concent 85% C demonstrate radioresistance compared to cells irradiated at 40 un. Concent 85% C by a factor of 1.59. It is suggested that low temperature results in protection rather than enhances recovery. The nature of this protection is not known but it is thought to be associated closely with slowed rate processes and recombination of molecules in the metionic state before deieterious reactions can take place. (auth)