Can directed activity improve mobility in Huntington's disease?
Can directed activity improve mobility in Huntington's disease?
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DOI：
10.1016/j.brainresbull.2006.10.021
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发表时间：
2007-04-30
影响因子：
3.8
通讯作者：
Rosser, A. E.
中科院分区：
文献类型：
--
作者：
Busse, M. E.;Rosser, A. E.
亨廷顿氏病是一种遗传性中枢神经系统疾病，导致活动性和认知能力的进行性恶化，也影响行为。迄今为止，还没有改善疾病的干预措施，尽管在旨在了解疾病的病理基础以确定潜在治疗方法的研究方面取得了相当大的进展。然而，重要的是不要忽视目前可用的治疗战略，包括康复方法。到目前为止，几乎没有工作来探索这种方法的潜力，在这里，我们强调需要在这方面进行更系统的研究，以及需要良好的客观评估工具和潜在的作用，康复和训练可能在新的治疗方案的应用。(c)2007年由Elsevier Inc.出版
Huntington's disease is an inherited disorder of the CNS that results in progressive deterioration of mobility and cognition and also affects behaviour. There are no disease-modifying interventions available to date, although there has been considerable progress in research directed at understanding the pathological basis of the disease with a view to identifying potential treatments. It is however important not to overlook currently available treatment strategies, including rehabilitation approaches. There has been little work to date to explore the potential of such approaches and here we highlight the need for more systematic studies in this area as well as the need for good objective assessment tools and the potential role that rehabilitation and training may have in the application of novel treatment options. (c) 2007 Published by Elsevier Inc.