Molecular characterization of toxin A-negative, toxin B-positive variant strains of Clostridium difficile isolated in Korea
Molecular characterization of toxin A-negative, toxin B-positive variant strains of Clostridium difficile isolated in Korea
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DOI：
10.1016/j.diagmicrobio.2010.01.007
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发表时间：
2010-06-01
影响因子：
2.9
通讯作者：
Lee, Kyungwon
中科院分区：
文献类型：
--
作者：
Kim, Sue Jung;Kim, Heejung;Lee, Kyungwon
A（-）B（+）艰难梭菌菌株在韩国很普遍。我们对韩国82株A（-）B（+）临床分离株进行了脉冲场凝胶电泳（PFGE）、聚合酶链反应核糖体分型和毒素分型。PFGE在3种方法中显示出最高的区分能力。PFGE结果显示，克隆体的持续存在表明该克隆体已适应了医院环境。(C)2010年爱思唯尔公司All rights reserved.
A(-)B(+) Clostridium difficile strains are prevalent in Korea. We performed pulsed-field gel electrophoresis (PFGE), polymerase chain reaction ribotyping, and toxinotyping in 82 A(-)B(+) clinical isolates in Korea. PFGE showed highest discriminatory capability among the 3 methods. By PFGE, persistence of a clone was found, suggesting this clone has adapted to the hospital environment. (C) 2010 Elsevier Inc. All rights reserved.