A Pilot Study of a Cognitive-Behavioral Treatment for Anxiety and Depression in Patients With Parkinson Disease
A Pilot Study of a Cognitive-Behavioral Treatment for Anxiety and Depression in Patients With Parkinson Disease
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DOI：
10.1177/0891988715588831
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发表时间：
2015-09-01
影响因子：
2.6
通讯作者：
Stanley, Melinda A.
中科院分区：
文献类型：
--
作者：
Calleo, Jessica S.;Amspoker, Amber B.;Stanley, Melinda A.
帕金森病（PD）患者的焦虑和抑郁通常未被识别或治疗不足。认知行为疗法（CBT）是有效的，但有限的证据支持其用于PD患者的焦虑和抑郁。16例具有显著焦虑和/或抑郁症状的PD患者被分配到CBT或加强常规护理。在基线、治疗后和1个月随访时进行评估。CBT干预包括焦虑，抑郁和健康生活与PD症状的工具。根据患者的偏好，通过电话或亲自进行个别治疗。治疗是可行的，参与者选择67%的会议通过电话和80%完成治疗。从基线到治疗后和从基线到1个月随访的评分变化的组间效应量较大（治疗后：抑郁症d = 1.49，焦虑症d = 1.44; 1个月随访：抑郁症d = 0.73，焦虑症d = 1.24），尽管只有抑郁症的治疗后效应量是显著的。该试点CBT方案对PD患者的焦虑和抑郁治疗是可行的。
Anxiety and depression often remain unrecognized or inadequately treated in patients with Parkinson disease (PD). Cognitive-behavioral therapy (CBT) is effective, but limited evidence supports its use for anxiety and depression in patients with PD. Sixteen patients with PD having significant anxiety and/or depressive symptoms were assigned to CBT or enhanced usual care. Assessments occurred at baseline, posttreatment, and 1-month follow-up. The CBT intervention included tools for anxiety, depression, and healthy living with PD symptoms. Individual sessions were delivered by telephone or in person, based on patient preference. Treatment was feasible with participants choosing 67% of sessions by telephone and 80% completed treatment. The between-group effect sizes for change scores from baseline to posttreatment and baseline to 1-month follow-up were large (posttreatment: d = 1.49 for depression and 1.44 for anxiety; 1-month follow-up: d = .73 for depression and 1.24 for anxiety), although only the posttreatment effect size for depression was significant. This pilot CBT program is feasible for treatment of anxiety and depression in patients with PD.