Antioxidant, alpha glucosidase and antibacterial evaluation of Syzygium mytifolium (Roxb.) Walp
Antioxidant, alpha glucosidase and antibacterial evaluation of Syzygium mytifolium (Roxb.) Walp
复制标题
蒲桃抗氧化、α-葡萄糖苷酶活性及抗菌活性评价沃尔普
DOI：
10.14719/pst.2021.8.2.1113
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发表时间：
2021-01-01
影响因子：
0.9
通讯作者：
Abdulrahman, Mahmoud Dogara
中科院分区：
文献类型：
--
作者：
Abdulrahman, Mahmoud Dogara
多年来，药用植物一直是对抗和治疗传染病和健康障碍的主要来源。探索廉价且安全的抗氧化剂和抗生素的新来源。 Syzygium mytifolium (Roxb.) Walp 不同提取物的抗氧化和抗菌潜力。通过 1,1-二苯基-2-苦三酰肼 (DPPH)、铁还原抗氧化能力 (FRAP)、α-葡萄糖苷酶抑制、纸片扩散和琼脂孔方法进行评估。蒲桃的叶、树皮、根和整株植物分别用乙醇、甲醇和水等不同溶剂提取，得到粗提物。其中，乙醇提取物在自由基清除活性、还原能力和α-葡萄糖苷酶抑制方面表现出较高的抗氧化活性，分别为1.84μg/ml、40.2mmol/gm和14.34μg/ml。植物的所有测试部分都对细菌病原体表现出中等至较高范围的抗菌活性，抑制范围在2-27.8毫米之间。 Syzygium mytifolium 将成为开发抗氧化剂补充剂和抗生素的非常好的来源，以应对传染性病原体和改善健康状况。
Medicinal plants have been the major source of combating and treating infectious diseases and health disorders throughout the ages. To explore new sources of inexpensive and safe antioxidants and antibiotics. The antioxidant and antibacterial potential of different extracts Syzygium mytifolium (Roxb.) Walp. were evaluated through 1,1-Diphenyl-2-Picryl Hydrazyl (DPPH), ferric reducing antioxidant power (FRAP), alpha-glucosidase inhibition, disk diffusion and agar well methods. The leaves, bark, root and whole plant of Syzygium mytifolium were extracted with various solvents viz ethanol, methanol and aqueous to give crude extracts, respectively. Among all, the ethanolic extract showed high antioxidant activity in terms of radical scavenging activity, reducing power and alpha-glucosidase inhibition at 1.84 mu g/ml, 40.2 mmol/gm and 14.34 mu g/ml, respectively. All the tested parts of the plant exhibited moderate to higher range of antibacterial activity against bacterial pathogens with the inhibition zones ranged between 2-27.8 mm. Syzygium mytifolium will serve as a very good source for the development of antioxidant supplements and antibiotics for addressing infectious pathogens and improvement of health status.