Study of the buffering capacity, pH and salivary flow rate in type 2 well-controlled and poorly controlled diabetic patients.
Study of the buffering capacity, pH and salivary flow rate in type 2 well-controlled and poorly controlled diabetic patients.
复制标题
控制良好和控制不良的2型糖尿病患者的缓冲能力、pH和唾液流量的研究。
DOI：
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发表时间：
2007
影响因子：
1.6
通讯作者：
J. Nicolau
中科院分区：
文献类型：
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作者：
Maria José Bernardi;A. Reis;A. Loguércio;R. Kehrig;M. Leite;J. Nicolau
目的
这项研究测量了巴西南部三个城市代谢控制良好和不良的 2 型糖尿病患者的唾液流量、pH 值和缓冲能力，并与同一城市的健康个体进行了比较。
材料和方法
通过机械刺激收集全部唾液并测量缓冲能力和葡萄糖水平。禁食12小时后采集血液并测定葡萄糖和糖化血红蛋白浓度。通过单向方差分析和 Student-Newman-Keuls (alpha= 0.05) 分析数据。
结果
与健康个体相比，无论代谢控制良好还是不良，2 型糖尿病患者的血流量均较低 (p < 0.05)。两个糖尿病患者组（即代谢控制良好和不良）的唾液葡萄糖浓度均高于对照组（p < 0.05）。
结论
高血糖的代谢控制不足以改善唾液流速或唾液葡萄糖浓度。
PURPOSE
This study measured the flow rate, pH and buffering capacity of saliva from well- and poorly metabolically controlled Type 2 diabetic patients in three cities of the southern part of Brazil, compared with healthy individuals from the same cities.
MATERIALS AND METHODS
Whole saliva was collected by mechanical stimulation and buffering capacity and glucose level were measured. Blood was collected after 12 hours fasting and glucose and glycosylated haemoglobin concentrations were determined. The data were analysed by one-way ANOVA and Student-Newman-Keuls (alpha= 0.05).
RESULTS
The flow rate was lower in the Type 2 diabetic patients, regardless of whether they were well or poorly metabolically controlled, compared with healthy individuals (p < 0.05). Salivary glucose concentration was higher in both diabetic patient groups, i.e. well and poorly metabolically controlled, than in the control (p < 0.05).
CONCLUSION
The metabolic control of hyperglycaemia was not sufficient to improve the salivary flow rate or the salivary glucose concentration.