LHRH-IMMUNOREACTIVE STRUCTURES IN THE SHEEP BRAIN
LHRH-IMMUNOREACTIVE STRUCTURES IN THE SHEEP BRAIN
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DOI：
10.1007/bf00489916
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发表时间：
1988-01-01
期刊：
影响因子：
--
通讯作者：
DUBOIS, MP
中科院分区：
文献类型：
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作者：
CALDANI, M;BATAILLER, M;DUBOIS, MP
含有促黄体生成激素释放激素（LHRH）的神经结构的特点是在成年母羊和雌性羔羊的大脑。三种抗LHRH抗血清用于免疫荧光或免疫过氧化物酶法。在我们的制备中，所有三个都给出了相同的结果，以标记细胞的数量表示（整个大脑中约有2500个）。结果发现，LHRH免疫反应阳性细胞95%位于视前-下丘脑区，其中50%的胞体主要位于终板血管器（OVLT）周围;它们也被发现在嗅结节和内侧隔的内侧部分的更前部（14%），下丘脑前部和外侧（16%）以及下丘脑内侧基底部（15%）的位置更靠后。起源于整个视前-下丘脑群各部分的纤维到达OVLT和正中隆起。其余的细胞（5%）和纤维被发现在不同的tel-，di-和中脑区域。
Neural structures containing luteinizing hormone-release hormone (LHRH) are characterized in adult ewe and female lamb brains. Three anti-LHRH antisera are used in an immunofluorescent or immunoperoxidase method. On our preparations, all three gave the same results, expressed as number of labelled cells (about 2500 in a whole brain). It was found that 95% of the LHRH-immunoreactive cells are located in the preoptico-hypothalamic area, where cell bodies are localized mainly (50%) in the area surrounding the organum vasculosum of the lamina terminalis (OVLT); they are also found in a more anterior section of the medial part of the olfactory tubercle and the medial septum (14%), in a more posterior situation in the anterior and lateral hypothalamus (16%), and in the mediobasal hypothalamus (15%). Fibres originating in various part of the whole preoptico-hypothalamic group reach the OVLT and the median eminence. The remaining cells (5%) and fibres are found in various tel-, di-, and mesencephalic areas.