Development of the asthma control test: A survey for assessing asthma control

Development of the asthma control test: A survey for assessing asthma control
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DOI:
10.1016/j.jaci.2003.09.008
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发表时间:
2004-01-01
影响因子:
14.2
通讯作者:
Pendergraft, TB
Pendergraft, TB
中科院分区:
医学1区
文献类型:
--
作者:
Nathan, RA;Sorkness, CA;Pendergraft, TB

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背景:哮喘指南指出,治疗的目标应该是最佳的哮喘控制。在时间和资源有限的繁忙临床实践中,需要一种简单的方法来评估哮喘控制情况,无论是否进行肺功能测试。目的:本文的目的是描述哮喘控制测试(ACT)的发展,这是一种基于患者的工具,用于识别控制不佳的哮喘患者。方法:对471例哮喘专科医生办公室的哮喘患者进行22项问卷调查。还收集了专家在肺活量测定后对哮喘控制的评分。逐步回归方法被用来选择与专家对哮喘控制的评分相关的最大判别有效性的条目子集。计算ACT量表的内部一致性信度,并进行判别效度检验。采用Logistic回归方法和受试者操作特征分析方法对ACT的治疗效果进行研究。ACT量表的内部一致性信度为0.84。ACT量表得分在专家对哮喘控制的评分不同的患者组之间进行区分,IF=34.5,P
Background: Asthma guidelines indicate that the goal of treatment should be optimum asthma control. In a busy clinic practice with limited time and resources, there is need for a simple method for assessing asthma control with or without lung function testing.Objectives: The objective of this article was to describe the development of the Asthma Control Test (ACT), a patient-based tool for identifying patients with poorly controlled asthma. Methods: A 22-item survey was administered to 471 patients with asthma in the offices of asthma specialists. The specialist's rating of asthma control after spirometry was also collected. Stepwise regression methods were used to select a subset of items that showed the greatest discriminant validity in relation to the specialist's rating of asthma control. Internal consistency reliability was computed, and discriminant validity tests were conducted for ACT scale scores. The performance of ACT was investigated by using logistic regression methods and receiver operating characteristic analyses.Results: Five items were selected from regression analyses. The internal consistency reliability of the 5-itern ACT scale was 0.84. ACT scale scores discriminated between groups of patients differing in the specialist's rating of asthma control IF = 34.5, P