Ultrasound-guided paravertebral blockade reduced perioperative opioids requirement in pancreatic resection: A randomized controlled trial.
Ultrasound-guided paravertebral blockade reduced perioperative opioids requirement in pancreatic resection: A randomized controlled trial.
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超声引导椎旁阻滞减少胰腺切除术围术期阿片类药物的需求：一项随机对照试验
DOI：
10.3389/fsurg.2022.903441
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发表时间：
2022
影响因子：
1.8
通讯作者：
Xu, Tao
中科院分区：
文献类型：
--
作者：
Han, Ye;Dai, Yuanqiang;Shi, Yaping;Zhang, Xiaoxiu;Xia, Boyang;Ji, Qiufang;Yu, Xiya;Bian, Jinjun;Xu, Tao
Perioperative opioid use for pain control has been found to be associated with side effects and adverse prognosis. In this study, we hypothesized that paravertebral block could reduce the consumption of opioids during pancreatic resection surgery. We conducted a prospective, randomized trial. Patients with resectable pancreatic cancer were randomly assigned to one of the two groups: those who received bilateral paravertebral block combined with general anesthesia [bilateral paravertebral blockade (PTB) group] or those who received only general anesthesia (Control group). The primary endpoint was the perioperative consumption of opioids (sufentanil and remifentanil). The main secondary endpoints were pain scores, complications, and serum cytokine levels. A total of 153 patients were enrolled in the study and 119 cases were analyzed. Compared to the control group, patients in PTB patients had significantly lower perioperative (30.81 vs. 56.17 µg), and intraoperative (9.58 vs. 33.67 µg) doses of sufentanil (both p < 0.001). Numerical rating scale scores of pain were comparable between the two groups. No statistical differences in complications were detected. Bilateral paravertebral block combined with general anesthesia reduced the perioperative consumption of opioids by 45%. ChiCTR1800020291 (available on http://www.chictr.org.cn/).
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影响因子：
8.8
作者：
Lee, Lorri A.;Caplan, Robert A.;Domino, Karen B.
通讯作者：
Domino, Karen B.
影响因子：
1.3
作者：
Pawa, Amit;Wojcikiewicz, Thomas;El-Boghdadly, Kariem
通讯作者：
El-Boghdadly, Kariem
影响因子：
8.8
作者：
Holte, K;Foss, NB;Kehlet, H
通讯作者：
Kehlet, H
DOI：
10.3390/medicina54050075
发表时间：
2018-10-23
期刊：
Medicina (Kaunas, Lithuania)
影响因子：
--
作者：
Aydin G;Aydin O
通讯作者：
Aydin O
影响因子：
3.7
作者：
Pei L;Zhou Y;Tan G;Mao F;Yang D;Guan J;Lin Y;Wang X;Zhang Y;Zhang X;Shen S;Xu Z;Sun Q;Huang Y;Outcomes Research Consortium
通讯作者：
Outcomes Research Consortium