1H NMR study of the regioisomers of primary O-di- and trisubstituted α-cyclodextrins
1H NMR study of the regioisomers of primary O-di- and trisubstituted α-cyclodextrins
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初级 O-二取代和三取代 α-环糊精的区域异构体的 1H NMR 研究
DOI：
10.1246/bcsj.61.3409
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发表时间：
1988
期刊：
影响因子：
--
通讯作者：
H. Sakate
中科院分区：
文献类型：
--
作者：
Y. Matsui;M. Fujie;H. Sakate
双和三[C（6）-O-磺酰化] α-环糊精的区域异构体以令人满意的产率转化为相应的C（6）-吡啶衍生物，得到了可用于区域异构体测定的特征1H NMR信号裂解图。带正电的吡啶基团之间的静电排斥相互作用在某些区域异构体的1H NMR信号的显着分裂中起着重要的作用。
The regioisomers of bis- and tris[C(6)-O-sulfonylated] α-cyclodextrins were converted in satisfactory yields to the corresponding C(6)-pyridinio derivatives, which afforded the characteristic splitting patterns of 1H NMR signals available for a regioisomer determination. Electrostatic repulsive interactions between the positively charged pyridinio groups play an important role in the remarkable splitting of the 1H NMR signals observed for some regioisomers.