Effect of PTSD diagnosis and contingency management procedures on cocaine use in dually cocaine- and opioid-dependent individuals maintained on LAAM: a retrospective analysis.
Effect of PTSD diagnosis and contingency management procedures on cocaine use in dually cocaine- and opioid-dependent individuals maintained on LAAM: a retrospective analysis.
复制标题
PTSD 诊断和应急管理程序对 LAAM 上可卡因和阿片类药物双重依赖个体使用可卡因的影响：回顾性分析。
DOI：
10.1111/j.1521-0391.2009.00025.x
复制
发表时间：
2010
期刊：
影响因子：
--
通讯作者：
Oliveto,Alison
中科院分区：
文献类型：
--
作者：
Mancino,MichaelJ;McGaugh,Janette;Feldman,Zachary;Poling,James;Oliveto,Alison
这项随机临床试验回顾性研究了创伤后应激障碍（PTSD）和应急管理（CM）对阿片类药物和可卡因依赖者使用可卡因的影响，这些人接受高剂量或低剂量LAAM，随机分配到CM或轭式对照条件。在非应急条件下，与PTSD患者相比，无PTSD患者的尿液中肌酐阳性率随着时间的推移下降得更快。在患有PTSD的参与者中，与非偶然条件相比，CM导致更少的可卡因阳性尿液。这表明，与没有PTSD的人相比，CM可能有助于改善阿片类药物和可卡因依赖的PTSD患者的潜在不良结局。
This randomized clinical trial retrospectively examined the effect of post‐traumatic stress disorder (PTSD) and contingency management (CM) on cocaine use in opioid and cocaine dependent individuals maintained on high or low‐dose LAAM randomly assigned to CM or a yoked‐control condition. Cocaine‐positive urines decreased more rapidly over time in those without PTSD versus those with PTSD in the noncontingency condition. In participants with PTSD, CM resulted in fewer cocaine‐positive urines compared to the noncontingent condition. This suggests that CM may help improve the potentially worse outcomes in opioid‐ and cocaine‐dependent individuals with PTSD compared to those without PTSD. (Am J Addict 2010;00:1–9)