Cardiovascular reactivity to stress in black male offspring of hypertensive parents.
Cardiovascular reactivity to stress in black male offspring of hypertensive parents.
复制标题
高血压父母的黑人男性后代的心血管对应激的反应。
DOI：
10.1097/00006842-199107000-00007
复制
发表时间：
1991
影响因子：
3.3
通讯作者：
Gilbert,DC
中科院分区：
文献类型：
--
作者：
Johnson,EH;Nazzaro,P;Gilbert,DC
将20名父母有高血压史的黑人男性的前臂血流量（FABF）和其他心血管反应与18名父母没有高血压史的黑人男性的反应进行比较。结果显示，高血压父母的儿子在初始评估时的收缩压和舒张压均高于正常父母的儿子，并且自测的家庭收缩压也明显高于正常父母的儿子。高血压父母的儿子在智力挑战和冷压时的收缩压反应高于正常父母的儿子，但在舒张压、心率（HR）、FABF或前臂血管阻力（FAVR）对应激源的反应方面没有组间差异。高血压父母的儿子对应激源的HR和FABF反应呈显著正相关。最后，研究结果表明，两组受试者对冷压（一种引起α -肾上腺素能活动的痛苦任务）的BP和FAVR反应明显高于对智力挑战（一种引起β -肾上腺素能活动的任务）的反应。这些结果的含义是根据目前的研究表明，黑人可能有更大的倾向于血压反应介导的-肾上腺素能增加血管阻力。
The forearm blood flow (FABF) and other cardiovascular responses of 20 black men with a parental history of hypertension were compared with the responses of 18 black men without a parental history of hypertension. The results showed that sons of hypertensive parents had higher systolic (SBP) and diastolic (DBP) blood pressure than sons of normotensive parents during the initial assessment as well as significantly higher self-determined home SBP. Sons of hypertensive parents had higher SBP responses than sons of normotensive parents during mental challenge and the cold pressor, but there were no group differences in DBP, heart rate (HR),(FABF), or forearm vascular resistance (FAVR) responses to the stressors. Significant positive correlations between HR and FABF responses to the stressors were observed for sons of hypertensive parents. Finally, the results showed that the BP and FAVR responses to the cold pressor (a painful task that elicits alpha-adrenergic activity) were significantly higher than responses to mental challenge (a task that elicits beta-adrenergic activity) for both groups. The implications of these results are discussed in light of current research suggesting that blacks may have a greater tendency toward BP responses mediated by alpha-adrenergic increases in vascular resistance.