MELANOCYTE SYSTEM OF ENDOLYMPHATIC DUCT AND SAC
MELANOCYTE SYSTEM OF ENDOLYMPHATIC DUCT AND SAC
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DOI：
10.1177/000348947808700205
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发表时间：
1978-01-01
影响因子：
1.4
通讯作者：
GUSSEN, R
中科院分区：
文献类型：
--
作者：
GUSSEN, R
本文观察了64例114侧颞骨内淋巴管和囊周围的黑素细胞。样本来自高加索人（104），东方人（6）和黑人（4）。在9岁以上的人的标本中，79%的人在内淋巴管和囊周围显示出黑化的黑素细胞，偶尔也在邻近骨骼的血管周围。这些人占高加索人的74%，占黑人和东方人的75%。在偶见的上皮衬里细胞和管腔内的巨噬细胞型细胞中观察到色素颗粒。在6例梅尼埃病患者（均来自白人）中的5例、5例既往有中耳炎的患者（其中2例来自黑人女性）中的5例、老年性耳聋、转移性癌（4例成人东方患者中的3例）、慢性中耳炎、耳硬化症和淋巴瘤患者的偶见标本以及几例明显正常的标本中，均观察到重度黑化的黑素细胞。黑化的程度与特定的疾病过程没有明确的相关性。
One hundred fourteen human temporal bones from 64 individuals were studied for the presence of melanized melanocytes about the endolymphatic duct and sac. Specimens were from Caucasians (104), Orientals (6) and Negroes (4). Of the specimens from people above nine years of age 79% demonstrated melanized melanocytes about the endolymphatic duct and sac, as well as occasionally about blood vessels in the adjacent bone. These represented 74% of the Caucasian and 75% of the Negro and Oriental individuals. Pigment granules were noted in occasional epithelial lining cells and in macrophage-type cells within the lumen. Heavily melanized melanocytes were noted in five of six specimens of Ménière's disease (all from Caucasian individuals), five of five specimens with previous labyrinthitis (two of which were from a Negro woman), and in occasional specimens from patients with presbycusis, metastatic carcinoma (three of the four adult Oriental patients), chronic otitis media, otosclerosis and lymphoma, as well as in several apparently normal specimens. No clear cut correlation of degree of melanization with specific disease processes can be discerned.