Evaluation of Mapleson systems for administration of inhaled nitric oxide
Evaluation of Mapleson systems for administration of inhaled nitric oxide
复制标题
用于吸入一氧化氮给药的 Mapleson 系统的评估
作者：
I. Kukita;K. Okamoto;Toshihide Sato;Y. Shibata;Kazuhiko Shiihara;K. Kikuta
为了评估使用Mapleson A、D和F系统手动控制通气期间吸入一氧化氮（NO）的安全性，我们使用化学发光分析仪检测了二氧化氮（NO2）的产生。NO浓度从0变化到百万分之19（ppm），并且在每个NO水平下，氧（O2）浓度从21%变化到100%。观察到NO2浓度增加时，无论是O2或NO浓度增加。当NO和O2浓度分别为19 ppm和100%时，Mapleson A、D和F系统的最大NO2浓度（平均值±标准差）分别为0.20±0.03、0.15±0.03和0.17±0.02 ppm。在4、8和12 ppm NO和100%O2下，Mapleson A系统的NO2浓度显著高于Mapleson D或F系统，在19 ppm NO和100%O2下，Mapleson D系统的NO2浓度显著高于Mapleson D系统。从NO2产生的角度来看，我们认为，Mapleson D和F系统比Mapleson A系统更安全时，需要手动控制通风。
To assess the safety of nitric oxide (NO) inhalation during manual-controlled ventilation using Mapleson A, D, and F systems, we examined nitrogen dioxide (NO2) production using a chemiluminescence analyzer. The NO concentration was changed from 0 to 19 parts per million (ppm), and at each level of NO the oxygen (O2) concentration was changed from 21% to 100%. The NO2 concentration was observed to increase when either the O2 or NO concentration was increased. The maximum NO2 concentrations (mean ± standard deviation) of the Mapleson A, D, and F systems were 0.20±0.03, 0.15±0.03, and 0.17±0.02 ppm, respectively, when the concentrations of NO and O2 were 19 ppm and 100%, respectively. The NO2 concentrations of the Mapleson A system were significantly higher than those of either the Mapleson D or F system at 4, 8, and 12 ppm NO and 100% O2, and than that of the Mapleson D system at 19 ppm NO and 100% O2. From the viewpoint of NO2 production, we suggest that the Mapleson D and F systems are safer than the Mapleson A system when manual-controlled ventilation is required.
影响因子：
8.8
作者：
Johns,RA
通讯作者：
Johns,RA
低剂量吸入一氧化氮长期治疗新生儿持续性肺动脉高压的临床反应。
DOI：
10.1016/s0022-3476(05)81551-3
发表时间：
1993
期刊：
The Journal of pediatrics
影响因子：
--
作者：
Kinsella,JP;Neish,SR;Ivy,DD;Shaffer,E;Abman,SH
通讯作者：
Abman,SH
影响因子：
158.5
作者：
ROSSAINT, R;FALKE, KJ;ZAPOL, WM
通讯作者：
ZAPOL, WM