A comparison of serum carbohydrate-deficient transferrin with other biological markers of excessive drinking.
A comparison of serum carbohydrate-deficient transferrin with other biological markers of excessive drinking.
复制标题
血清碳水化合物缺乏的转铁蛋白与过量饮酒的其他生物标志物的比较。
DOI：
--
复制
发表时间：
1988
影响因子：
2.1
通讯作者：
J. Mørland
中科院分区：
文献类型：
--
作者：
H. Gjerde;J. Johnsen;A. Bjørneboe;G. Bjørneboe;J. Mørland
在一项研究中，建议的生物标志物过量饮酒，血清碳水化合物缺乏转铁蛋白（CDT）进行了比较，血清丙氨酸氨基转移酶，碱性磷酸酶，淀粉酶，天冬氨酸氨基转移酶和γ谷氨酰转移酶的活动;血清浓度的高密度脂蛋白胆固醇;和红细胞平均细胞体积。分析数据进行了研究，在最近一个月的自我报告的酒精消费量为69名参与者。CDT被认为是过度饮酒的最敏感和最具体的标志物，也被认为是监测戒酒治疗下的最佳标志物。
In a study of suggested biological markers of excessive drinking, serum carbohydrate-deficient transferrin (CDT) was compared with serum activities of alanine aminotransferase, alkaline phosphatase, amylase, aspartate aminotransferase and gamma glutamyltransferase; serum concentrations of high-density lipoprotein cholesterol; and erythrocyte mean cellular volume. Analytical data were studied in relation to self-reported alcohol consumption during the latest month for the 69 participating subjects. CDT was found to be the most sensitive and most specific marker of excessive drinking, and was also found to be the best marker for monitoring abstinence under treatment of alcoholics.