DUAL INNERVATION OF MAMMALIAN URINARY BLADDER - A HISTOCHEMICAL STUDY OF DISTRIBUTION OF CHOLINERGIC AND ADRENERGIC NERVES
DUAL INNERVATION OF MAMMALIAN URINARY BLADDER - A HISTOCHEMICAL STUDY OF DISTRIBUTION OF CHOLINERGIC AND ADRENERGIC NERVES
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DOI：
10.1002/aja.1001190305
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发表时间：
1966-01-01
影响因子：
--
通讯作者：
SCHENK, EA
中科院分区：
文献类型：
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作者：
ELBADAWI, A;SCHENK, EA
本文用乙酰胆碱酯酶和去甲肾上腺素的特异性组化技术，研究了猫、狗、兔和大鼠膀胱的自体神经支配。胆固醇和肾上腺素能神经节细胞存在于整个膀胱壁的所有层中。大的胆碱能和肾上腺素能神经干在外被膜和前板深分支中走行进入肌层。终末胆碱能分支形成包围膀胱壁中每个平滑肌细胞的神经末梢丛。终末肾上腺素能纤维不太丰富，不形成神经丛，在肌层的不同水平和深度显示出区域性的数量变化。这些变化表明，膀胱的两个区域，即基部和体部，可以根据肌肉神经支配的差异来区分。在前板中，胆碱能神经和肾上腺素能神经分为上皮下深神经和上皮下浅神经。后者形成复杂性可变的网络并向上皮供应纤维。在整个膀胱壁中，血管具有双重胆碱能和肾上腺素能血管周围丛，纤维从血管周围丛延伸到中膜。虽然在所研究的物种中，神经支配的基本模式是相似的，但上皮和上皮下神经的相对丰度和排列存在一定的差异。肌层有一个统一的胆碱能和不同的肾上腺素能神经支配在不同的物种。
The pattern of autohomic innervation of the urinary bladder was studied in the cat, dog, rabbit and rat, using specific hlstochemtcal technics for acetylcholinesterase and nor-eplnephrine. Choltaerglc and adrenergic ganglion cells exist tn all layers throughout the bladder wall. Large chollnergic and adrenergic nerve trunks coursing in the adventltial coat and deep lamina proprla branch into the muscularis. The terminal chollnergic ramifications form a neurotermlnal plexus which surrounds every smooth muscle cell in the bladder wall. The terminal adrenergic fibers are less abundant, do not form a plexus, and show regional variations in number at different levels and depths of the muscularis. These variations suggest that 2 regions of the bladder, namely the base and body, may be distinguished on the basis of differences In muscular innervation. In the lamina proprla chollnergic and adrenergic nerves are grouped as deep and superficial subepithelial nerves. The latter form networks of variable complexity and supply fibers to the epithelium. Throughout the bladder wall, the blood vessels have a dual chollnergic and adrenergic perivascular plexus from which fibers extend into the media. Although the baste pattern of Innervation is similar in the species studied, certain variations exist in the relative abundance and arrangement of epithelial and subepithelial nerves. The muscularis has a uniform cholinergic and a variable adrenergic innervation in different species.