Intramolecular 1,5-H transfer reaction of aryl iodides through visible-light photoredox catalysis: a concise method for the synthesis of natural product scaffolds
Intramolecular 1,5-H transfer reaction of aryl iodides through visible-light photoredox catalysis: a concise method for the synthesis of natural product scaffolds
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可见光光氧化还原催化芳基碘化物的分子内1,5-H转移反应：一种合成天然产物支架的简明方法
DOI：
10.1039/c6cc02007k
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发表时间：
2016-01-01
影响因子：
4.9
通讯作者：
Xu, Peng-Fei
中科院分区：
文献类型：
--
作者：
Chen, Jian-Qiang;Wei, Yun-Long;Xu, Peng-Fei
本文报道了未活化的碘代芳烃经碘化反应生成的芳基自由基的分子内1，5-H转移反应。该方法具有操作简单、产率高、反应条件温和、官能团耐受性好等特点。利用这种方法，完成了（+/-）-蓝花苦素和（+/-）-毒扁豆碱的更简洁的形式合成。
The intramolecular 1,5-H transfer reaction of the aryl radicals generated from unactivated aryl iodides by photocatalysis is described. The features of this transformation are operational simplicity, excellent yields, mild reaction conditions, and good functional group tolerance. With this approach, a more concise formal synthesis of (+/-)-coerulescine and (+/-)-physovenine is accomplished.