Novel digital subtraction CT angiography based on 3D registration and refinement
Novel digital subtraction CT angiography based on 3D registration and refinement
复制标题
基于3D配准和细化的新型数字减影CT血管造影
DOI：
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发表时间：
2004
期刊：
影响因子：
--
通讯作者：
J. Ra
中科院分区：
文献类型：
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作者：
S. Kwon;Yong Sun Kim;Tae;Dong Ik Kim;J. Ra
使用高分辨率CT图像的血管造影研究已成为血管疾病敏感检查的有用工具。然而，CT血管造影（CTA）不能直接了解血管结构，因为一些感兴趣的部分可以位于高密度颅底区域附近。本文提出了一种快速自动三维数字减影CT血管造影（DS-CTA）的新方法，以生成无伪影的血管造影图像。所提出的方法包括3D配准CT图像的CTA图像，减影和细化提取血管。为了实现高效率、高精度的三维配准，采用了基于归一化互信息的配准算法，并通过引入一种新的度量标准，发展了一种快速配准算法。与传统的配准方法相比，本文提出的快速配准算法的加速比约为1.74~3.01。为了提高第二步减影图像的质量，提出了一种新的三维细化算法，有效地去除不必要的残留。七个临床CT/CTA头部数据集的实验结果表明，脑血管是很好地提取CTA图像，几乎没有损失。典型的处理时间约为3~9分钟，具体取决于具有2.4GHz CPU的PC中的图像大小。
Angiographic investigation using high-resolution CT images has become a useful tool for the sensitive examination of vascular diseases. However, CT angiography (CTA) does not allow a straightforward understanding of vascular structure, since some of interesting parts can be located near the high intensity skull base region. In this paper, a novel method for fast and automatic 3D digital subtraction CT angiography (DS-CTA) is presented to generate artifact-free angiograms. The proposed method consists of 3D registration to align a CT image to the CTA image, and subtraction and refinement to extract blood vessels. For efficient and accurate 3D registration, an NMI (normalized mutual information) based algorithm is adopted and its fast version is developed by introducing a new measure. The speed-up ratio of the proposed fast registration algorithm is about 1.74~3.01 compared with the conventional registration method. And to improve the subtracted image quality in the second step, a novel 3D refinement algorithm is suggested to effectively remove unwanted residuals. Experimental results of seven clinical CT/CTA head datasets demonstrate that cerebral vessels are well extracted from CTA images with almost no loss. The typical processing time is about 3~9 minutes depending on the image size in a PC with a 2.4GHz CPU.
影响因子：
1.3
作者：
West, J;Fitzpatrick, JM;Woods, RP
通讯作者：
Woods, RP