Generator study of brainstem auditory evoked potentials by a radiofrequency lesion method in rats
Generator study of brainstem auditory evoked potentials by a radiofrequency lesion method in rats
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射频损伤法对大鼠脑干听觉诱发电位的发生器研究
作者：
T. Chen;S.
实验研究了大鼠脑干听觉诱发电位（BAEPs）的产生机制。采用立体定向射频凝固法单侧制作脑干听道离散病变，记录病变前后baep，观察病变改变。损伤对BAEP波的影响如下：(1)所有BAEP波均因听神经损伤而减弱或消除；(2)耳蜗核损伤后II波消失或振幅减弱；(3)上橄榄复合体病变后，III波明显减少或消失，IV波和V波也有一定影响；(4)与IV波和V波变化不一致相关的外侧小网膜病变显著减弱了III波的下波谷；(5)下丘损伤对脑波无明显影响。与其他手术损伤方法相比，使用立体定位的射频损伤方法被证明是一种更简单、更快速的方法来确定动物baep的产生。
SummaryThe generators of brainstem auditory evoked potentials (BAEPs) in rats were investigated experimentally. Discrete lesions of the brainstem auditory pathway were made unilaterally using a stereotaxic radiofrequency coagulation method, and the BAEPs were recorded before and after the lesions to observe the alterations. The waves of the BAEPs were affected by the lesions as follows: (1) all of the BAEP waves were attenuated or eliminated by a lesion of the auditory nerve; (2) wave II was abolished or attenuated in amplitude following a lesion of the cochlear nucleus; (3) marked reduction or abolition of wave III occurred with some effect on waves IV and V following lesions of the superior olivary complex; (4) the following trough in the wave III was significantly attenuated by lesions of the lateral lemniscus that were associated with inconsistent changes in waves IV and V; (5) no waves were affected significantly by a lesion of the inferior colliculus. The method of radiofrequency lesion using stereotaxic localization proved to be a simpler and more rapid procedure for determining the generators of BAEPs in animals than other surgical lesion methods.
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猫交叉橄榄耳蜗束的横切和听觉脑干反应。
影响因子：
1.4
作者：
O-Uchi,T;Igarashi,M;Kulecz,WB
通讯作者：
Kulecz,WB
DOI：
10.1016/0168-5597(86)90015-8
发表时间：
1986-09-01
期刊：
ELECTROENCEPHALOGRAPHY AND CLINICAL NEUROPHYSIOLOGY
影响因子：
--
作者：
MOLLER, AR;BURGESS, J
通讯作者：
BURGESS, J
多模态诱发电位对猫脑干病变的无创定位：与人类头部损伤数据的相关性。
影响因子：
4.1
作者：
Greenberg,RP;Stablein,DM;Becker,DP
通讯作者：
Becker,DP
DOI：
10.1016/0013-4694(83)90260-2
发表时间：
1983-10
期刊：
Electroencephalography and clinical neurophysiology
影响因子：
--
作者：
Shin-Ichi Wada;A. Starr
通讯作者：
Shin-Ichi Wada;A. Starr
DOI：
10.1016/0013-4694(83)90259-6
发表时间：
1983
期刊：
Electroencephalography and clinical neurophysiology
影响因子：
--
作者：
Wada,SI;Starr,A
通讯作者：
Starr,A