Neuropsychiatric consequences of AIDS

Neuropsychiatric consequences of AIDS
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艾滋病的神经精神后果

DOI:
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发表时间:
1988
影响因子:
11.2
通讯作者:
H. Lane
H. Lane
中科院分区:
医学1区
文献类型:
--
作者:
D. Rubinow;Christine H. Berrettini;P. Brouwers;H. Lane

文献摘要

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作为一项正在进行的研究的一部分,神经心理学测试已被管理13例临床获得性免疫缺陷综合征,9人免疫缺陷病毒血清阳性患者,4血清阳性慢性活动性肝炎患者,5血清阴性慢性活动性肝炎患者,和6名健康对照。与早期患者组和对照组的研究结果一致,获得性免疫缺陷综合征患者在各种认知测试中的得分明显较低。虽然获得性免疫缺陷综合征组目前没有教育匹配,但结果与语言功能和时间,自定进度的表现受损一致。获得的测试结果可能反映局灶性和全球认知功能障碍,以及动机减退,获得性免疫缺陷综合征患者相对于血清阳性患者或对照。
As part of a study in progress, neuropsychological tests have been administered to 13 patients with clinical acquired immunodeficiency syndrome, 9 human immunodeficiency virus–seropositive patients, 4 seropositive patients with chronic active hepatitis, 5 seronegative patients with chronic active hepatitis, and 6 healthy controls. Consistent with findings in earlier patient and control groups, the acquired immunodeficiency syndrome patients had substantially lower scores on a variety of cognitive tests. Although the acquired immunodeficiency syndrome group is not education‐matched at present, the results are nonetheless consistent with impairments of language function and timed, self‐paced performance. Test results obtained may reflect focal and global cognitive impairment as well as motivational decrements in patients with the acquired immunodeficiency syndrome relative to seropositive patients or controls.