Lower-extremity muscle cross-sectional area after incomplete spinal cord injury
Lower-extremity muscle cross-sectional area after incomplete spinal cord injury
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DOI：
10.1016/j.apmr.2006.02.028
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发表时间：
2006-06-01
影响因子：
4.3
通讯作者：
Vandenborne, Krista
中科院分区：
文献类型：
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作者：
Shah, Prithvi K.;Stevens, Jennifer E.;Vandenborne, Krista
目的：(1)量化不完全性脊髓损伤（SCI）患者下肢肌肉的骨骼肌大小，(2)评估受累下肢肌肉大小的差异，(3)确定不完全性脊髓损伤后运动状态（使用轮椅进行社区活动与不使用轮椅进行社区活动）对肌肉大小的影响，(4)确定不完全性脊髓损伤后个体肌肉之间是否发生差异萎缩。设计：病例对照研究。环境：大学研究环境。参与者：17名不完全性脊髓损伤患者和17名年龄、性别、体重和身高匹配的非损伤对照组。干预措施：不适用。主要观察指标：单个下肢肌肉（比目鱼肌、腓肠肌内侧、腓肠肌外侧、胫骨前肌、股四头肌、腘绳肌）的最大横截面积（CSA）通过磁共振成像评估。结果：总体而言，与对照组相比，不完全性脊髓损伤受试者受影响下肢肌肉的平均肌肉CSA明显更小（24%-31%）
Objectives: (1) To quantify skeletal muscle size in lower-extremity muscles of people after incomplete spinal cord injury (SCI), (2) to assess differences in muscle size between involved lower limbs, (3) to determine the impact of ambulatory status (using wheelchair for community mobility vs not using a wheelchair for community mobility) on muscle size after incomplete SCI, and (4) to determine if differential atrophy occurs among individual muscles after incomplete SCI.Design: Case-control study.Setting: University research setting.Participants: Seventeen people with incomplete SCI and 17 age-, sex-, weight-, and height-matched noninjured controls.Interventions: Not applicable.Main Outcome Measures: Maximum cross-sectional area (CSA) of individual lower-extremity muscles (soleus, medial gastrocnemius, lateral gastrocnemius, tibialis anterior, quadriceps femoris, hamstrings) as assessed by magnetic resonance imaging.Results: Overall, subjects with incomplete SCI had significantly smaller (24%-31%) average muscle CSA in affected lower-extremity muscles as compared with control subjects (P