Allergic contact dermatitis from strawberry lipsalve
Allergic contact dermatitis from strawberry lipsalve
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草莓润唇膏引起的过敏性接触性皮炎
DOI：
10.1111/j.1600-0536.1996.tb02149.x
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发表时间：
1996
影响因子：
5.5
通讯作者：
C. Lawrence
中科院分区：
文献类型：
--
作者：
A. Taylor;L. Lever;C. Lawrence
病例1，一位37岁的家庭主妇，有两个月的口周湿疹病史，主要位于上嘴唇。嘴唇有水肿和红斑，周边向外延伸，有红边。她报告的唯一相关产品是一种牙膏--氟乐果Gelkam。2年前，她对肉桂醛、美国L-101和钴的斑贴试验呈阳性。对目前的标准系列、牙医系列、面部和化妆品系列以及Gelkam进行了贴片测试。尽管之前的结果是积极的，但这些都是负面的。上唇口腔粘膜活检显示为接触性皮炎的组织学特征。她接受了无肉桂、无镍和低过敏性的饮食，而没有任何改善。在评论中，她提到了她长期使用的Boots草莓唇膏，含有令人舒缓的洋甘菊提取物。斑贴试验呈阳性。对唇膏的个别成分的斑贴试验对草莓味道(49392)呈阳性，但对其他成分不呈阳性(表1)。随后对草莓口味的各个成分进行了斑贴试验(表2)，对纯麦芽酚I%宠物观察到阳性反应：30名对照对相同的制剂呈阴性。唇膏的使用停止了，唇炎在几天内就消失了。在接下来的12个月里，它没有复发。
Case Reports Case no. 1 A 37-year-old housewife presented with a 2-month history of perioral eczema mainly on the upper lip. The lips were oedematous and erythematous, with peripheral scaling outwith the vermilion border. The only relevant product that she reported was Fluorigard Gelkam, a toothpaste. 2 years earlier, she had been patch-test-positive to cinnamic aldehyde, Amerchol L-101 and cobalt. Patch tests were carried out to the current standard series, a dentists' series, face and cosmetics series and Gelkam. Despite previous positive results, these were all negative. Biopsy of the oral mucosa of the upper lip showed histological features of contact dermatitis. She undertook cinnamon-free, nickel-free and hypoallergenic diets, in turn, with no improvement. At review, she mentioned her long-term use of Boots Strawberry Lip Salve, with soothing extract of camomile. A patch test was positive. Patch tests to the individual constituents of the lipsalve were positive to the strawberry flavour ( 49392) I% pet., but not to the others (Table 1). Patch tests were subsequently carried out to the individual constituents of the strawberry flavour (Table 2), and a positive reaction was observed to pure maltol I% pet.: 30 controls were negative to the same preparation. The use of the lipsalve was stopped and the cheilitis resolved within a few days. It has not recurred in the following 12 months.