SAMPLE-SIZE FORMULAS FOR INTERVENTION STUDIES WITH THE CLUSTER AS UNIT OF RANDOMIZATION
SAMPLE-SIZE FORMULAS FOR INTERVENTION STUDIES WITH THE CLUSTER AS UNIT OF RANDOMIZATION
复制标题
DOI：
10.1002/sim.4780071113
复制
发表时间：
1988-11-01
影响因子：
2
通讯作者：
HSIEH, FY
中科院分区：
文献类型：
--
作者：
HSIEH, FY
本文介绍了从使用群集作为随机化单位的干预研究中获得的连续和二分终点的样本量公式。该公式提供了所需的集群数或所需的每个集群的个体数时，其他数量。建议的公式来自学生的t检验与使用集群汇总措施和方差，包括内和集群之间的组件。提供功效轮廓以帮助设计使用聚类随机化的干预研究。有和没有聚类分层的设计的样本量公式分别显示。
This paper presents sample size formulae for both continuous and dichotomous endpoints obtained from intervention studies that use the cluster as the unit of randomization. The formulae provide the required number of clusters or the required numer of individuals per cluster when the other number is given. The proposed formulae derive from Student''s t-test with use of cluster summary measures and a variance that consists of within and between cluster components. Power contours are provided to help in the design of intervention studies that use cluster randomization. Sample size formulae for designs with and without stratification of clusters appear separately.