Association between physical activity, occupational sitting time and mortality in a general population: An 18-year prospective survey in Tanushimaru, Japan
Association between physical activity, occupational sitting time and mortality in a general population: An 18-year prospective survey in Tanushimaru, Japan
复制标题
DOI：
10.1177/2047487318810020
复制
发表时间：
2020-05-01
影响因子：
8.3
通讯作者：
Fukumoto, Yoshihiro
中科院分区：
文献类型：
--
作者：
Sakaue, Akiko;Adachi, Hisashi;Fukumoto, Yoshihiro
目的众所周知，体育活动的减少与包括心血管事件和癌症在内的全因死亡的增加有关。很少有研究探讨职业久坐时间与死亡率之间的关系。因此，我们调查了这个问题在一般population.MethodsPhysical活动和职业坐着的时间进行了测量，在1999年使用Baecke体力活动问卷。调查问卷生成的指数在三个体力活动类别：工作，运动和休闲时间。通过将这三个指数相加来计算总体力活动指数。Baecke体力活动问卷能够评估职业坐姿时间。使用考克斯的比例风险回归models.ResultsWe招募了共1680名参与者，谁被随访15.9 +/- 3.8年的风险比和95%的置信区间（CI）进行计算。最终随访率为93%。随访期间，397例受试者死亡。在调整年龄和性别后，发现体力活动与死亡率之间存在显著的负相关（p < 0.0001）。与较低水平的体力活动相比，较高水平体力活动的死亡率校正风险比为0.85（95%CI：0.78-0.92）。较长的职业坐姿时间也与较高的死亡率显著相关（p < 0.01）。较长职业坐姿时间的死亡率校正风险比为1.16（95%CI：1.05-1.27）。这些发现在男性中观察到，但不是在femines.ConclusionsOur数据表明，较高水平的体力活动与癌症和心血管死亡的风险降低。此外，较长的职业坐姿时间与死亡率增加有关。
AimsIt is well known that a decline in physical activity is associated with an increase of all-cause death including cardiovascular events and cancer. Few studies have examined the association between occupational sitting time and mortality. Therefore, we investigated this issue in a general population.MethodsPhysical activity and occupational sitting time were measured using the Baecke physical activity questionnaire in 1999. The questionnaire generated indices in three physical activity categories: work, sport and leisure-time. A total physical activity index was calculated by adding these three indices. The Baecke physical activity questionnaire was able to evaluate occupational sitting time. Hazard ratios and 95% confidence intervals (CIs) were calculated using Cox's proportional hazard regression models.ResultsWe enrolled a total of 1680 participants, who were followed up for 15.9 +/- 3.8 years. The final follow-up rate was 93%. During the follow-up period, 397 subjects died. A significant inverse association (p < 0.0001) was found between physical activity and mortality after adjustment for age and sex. Compared with lower levels of physical activity, the adjusted hazard ratio for mortality at higher levels of physical activity was 0.85 (95% CI: 0.78-0.92). Longer occupational sitting time was also significantly associated with higher mortality (p < 0.01). The adjusted hazard ratio for mortality at longer occupational sitting time was 1.16 (95% CI: 1.05-1.27). These findings were observed in males, but not in females.ConclusionsOur data demonstrated that higher levels of physical activity are associated with a reduced risk of cancer and cardiovascular death. Further, longer occupational sitting time is associated with increased mortality.