Mediating links between maternal depression and offspring psychopathology: the importance of independent data
Mediating links between maternal depression and offspring psychopathology: the importance of independent data
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DOI：
10.1111/j.1469-7610.2004.00367.x
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发表时间：
2005-05-01
影响因子：
7.6
通讯作者：
Carlson, EA
中科院分区：
文献类型：
--
作者：
Burt, KB;Van Dulmen, MHM;Carlson, EA
背景：检查精神病理学代际传播的研究通常受限于依赖相同的人来获得关于感兴趣的多个结构的信息。为了抵消这一局限性，对高危青年进行了一项前瞻性的纵向研究，分析了数据，以检验父母教养和家庭环境因素在青春期后期母亲抑郁症状和子女精神病理之间起中介作用的假设。方法：来自明尼苏达州亲子纵向研究的184个家庭的数据。测量包括CES-D和Beck抑郁量表，家庭环境评级和家庭冲突量表，CBCL行为问题检查表和K-SADS精神症状评分。通过回归分析来检验家庭环境因素对母亲抑郁的中介作用。结果：使用单一信息者和时间点的分析显示，存在实质性调解的证据；然而，在跨越独立信息者和多个时间点的分析中，中介作用显著降低。研究发现，男性的父母教养和家庭环境因素与精神病理有关，而女性的母亲抑郁与精神病理更直接相关。结论：研究结果强调了独立数据对检验中介主张的重要性，并支持了男性和女性青年在精神病理学代际传播过程中存在差异的说法。
B ackground: Research examining intergenerational transmission of psychopathology is often limited by reliance on the same individuals for information on multiple constructs of interest. To counteract this limitation, data from a prospective, longitudinal study of at-risk youth were analyzed to test the hypothesis that parenting and family environmental factors mediate the association between maternal depressive symptoms and offspring psychopathology in late adolescence. Method: Data were taken from 184 families of the Minnesota Longitudinal Study of Parents and Children. Measures included the CES-D and Beck depression inventories, home environment ratings and a family conflict scale, and CBCL behavior problem checklist and K-SADS psychiatric symptom scores. Regression analyses were conducted to test for mediation of maternal depression effects by family environmental factors. Results: Analyses using a single informant and time point showed evidence for substantial mediation; however, in analyses spanning independent informants and multiple time points mediating effects were markedly reduced. Sex differences were found, in that parenting and family environmental factors related to psychopathology for males, whereas maternal depression was more directly related to psychopathology for females. Conclusions: Results emphasize the importance of independent data for testing mediational claims, and support claims that the processes involved in the intergenerational transmission of psychopathology are different for male and female youth.