Multi-slice computed tomography-assisted endoscopic transsphenoidal surgery for pituitary macroadenoma: a comparison with conventional microscopic transsphenoidal surgery

Multi-slice computed tomography-assisted endoscopic transsphenoidal surgery for pituitary macroadenoma: a comparison with conventional microscopic transsphenoidal surgery
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多层计算机断层扫描辅助内窥镜经蝶手术治疗垂体大腺瘤:与传统显微经蝶手术的比较

DOI:
10.1179/1743132815y.0000000078
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发表时间:
2015
影响因子:
1.9
通讯作者:
Y. Yoshimoto
Y. Yoshimoto
中科院分区:
医学4区
文献类型:
--
作者:
M. Tosaka;Tomohito Nagaki;Fumiaki Honda;Katsumasa Takahashi;Y. Yoshimoto

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Abstract Objectives: Intraoperative computed tomography (iCT) is a reliable method for the detection of residual tumour, but previous single-slice low-resolution computed tomography (CT) without coronal or sagittal reconstructions was not of adequate quality for clinical use. The present study evaluated the results of multi-slice iCT-assisted endoscopic transsphenoidal surgery for pituitary macroadenoma. Methods: This retrospective study included 30 consecutive patients with newly diagnosed or recurrent pituitary macroadenoma with supradiaphragmatic extension who underwent endoscopic transsphenoidal surgery using iCT (eTSS+iCT group), and control 30 consecutive patients who underwent conventional endoscope-assisted transsphenoidal surgery (cTSS group). The tumour volume was calculated by multiplying the tumour area by the slice thickness. Visual acuity and visual field were estimated by the visual impairment score (VIS). Results: The resection extent, (preoperative tumour volume – postoperative residual tumour volume)/preoperative tumour volume, was 98.9% (median) in the eTSS+iCT group and 91.7% in the cTSS group, and had significant difference between the groups (P = 0.04). Greater than 95 and >90% removal rates were significantly higher in the eTSS+iCT group than in the cTSS group (P = 0.02 and P = 0.001, respectively). However, improvement in VIS showed no significant difference between the groups. The rate of complications also showed no significant difference. Discussion: Multi-slice iCT-assisted endoscopic transsphenoidal surgery may improve the resection extent of pituitary macroadenoma. Multi-slice iCT may have advantages over intraoperative magnetic resonance imaging in less expensive, short acquisition time, and that special protection against magnetic fields is not needed.
快速连续静脉注射四种下丘脑释放激素作为正常受试者的垂体前叶功能联合测试。
DOI: 10.1210/jcem-60-4-623
发表时间: 1985
期刊: The Journal of clinical endocrinology and metabolism
影响因子: --
作者:
SheldonJr,WR;DeBold,CR;Evans,WS;DeCherney,GS;Jackson,RV;Island,DP;Thorner,MO;Orth,DN
通讯作者: Orth,DN
DOI: 10.1148/radiology.211.2.r99ma26477
发表时间: 1999-05
期刊: Radiology
影响因子: 19.7
作者:
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通讯作者: R. Schwartz;L. Hsu;T. Wong;D. Kacher;A. Zamani;P. Black;E. Alexander;P. Stieg;T. Moriarty