Cephalometric assessment of craniofacial morphology in Chinese patients with obstructive sleep apnoea
Cephalometric assessment of craniofacial morphology in Chinese patients with obstructive sleep apnoea
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DOI：
10.1053/rmed.2003.1494
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发表时间：
2003-06-01
影响因子：
4.3
通讯作者：
Ching, ASC
中科院分区：
文献类型：
--
作者：
Hui, DSC;Ko, FWS;Ching, ASC
目的：目的：比较阻塞性睡眠呼吸暂停（OSA）患者与非阻塞性睡眠呼吸暂停患者颅面形态的差异。方法：对94例（77例男性）伴有打鼾或其他症状的OSA患者进行多导睡眠图（PSG）头颅侧位X线片检查。严重OSA定义为夜间PSG睡眠呼吸暂停低通气指数（AHI）大于或等于10/h。比较有无明显OSA患者的头影测量数据。结果（平均值+/- SD）：有69例（56例男性）患有严重的OSA，平均年龄53 ± 12岁，体重指数（BMI）28.6 ± 5.0 kg/m2，AHI 36.5 ± 20.6/h，最低SaO（2）76 ± 14%。有25例（21例男性）没有明显的OSA，年龄和BMI相似。OSA患者下颌骨平面至舌骨的距离（MPH）和舌骨至C3椎体与颌后突连线的垂直距离（HHI）明显延长。OSA组鞍点至鼻根点至A点的角度（SNA）较小。MPH距离是显著OSA的唯一独立变量，比值比为3.47（95%CI 1.39-8.66）。BMI > 30 kg/m2的OSA患者MPH和SNA的降低更明显。结论：OSA患者和非窒息对照组的颅面形态存在显著差异。肥胖患者的舌骨位置偏前和上颌骨位置偏后可能使其更易发生严重的阻塞性睡眠呼吸暂停。(C)2003 Eisevier Science Ltd.保留所有权利。
Objective: To compare the differences in craniofacial morphology in Chinese patients with and without obstructive sleep apnoea (OSA), Method: We performed lateral cephalometric radiographs on 94 consecutive patients (77 males) referred with snoring or other symptoms suggestive of OSA for polysomnography (PSG). Significant OSA was defined as an apneoa-hypopnoeaindex (AHI) greater than or equal to 10/h of sleep on overnight PSG. The cephalometric data were compared between those with and without significant OSA. Results (mean +/- SD): There were 69 (56 males) with significant OSA with mean age 53 +/- 12 years, body mass index (BMI) 28.6 +/- 5.0 kg/m(2), AHI 36.5 +/- 20.6/h, and minimum SaO(2) 76 +/- 14%, There were 25 controls (21 males) without significant OSA with similar age and BMI. The mandibular plane to hyoid bone distance (MPH) and the perpendicular distance from hyoid bone to the line connecting C3 vertebra and retrognathion (HHI) were significantly longer in the OSA patients. The angle measurement from sella to nasion to point A (SNA) was smaller in the OSA group. MPH distance was the only independent variable for significant OSA with an odds ratio of 3.47 (95% Cl 1.39-8.66). Abnormalities of the MPH and SNA were more marked in the OSA patients with BMI > 30 kg/m(2). Conclusions: Significant differences in craniofacial morphology are noted between OSA patients and non-apnoeic controls. An inferiorly positioned hyoid bone and a retropositioned maxilla may predispose obese patients to more severe OSA. (C) 2003 Eisevier Science Ltd. All rights reserved.