Barriers to clinical trial participation as perceived by oncologists and patients.
Barriers to clinical trial participation as perceived by oncologists and patients.
复制标题
肿瘤学家和患者认为参与临床试验的障碍。
DOI：
10.6004/jnccn.2007.0067
复制
发表时间：
2007
期刊：
影响因子：
--
通讯作者：
P. Watts
中科院分区：
文献类型：
--
作者：
N. Meropol;J. Buzaglo;Jennifer Millard;N. Damjanov;Suzanne M. Miller;C. Ridgway;E. Ross;J. Sprandio;P. Watts
Although clinical trial research is required for the development of improved treatment strategies, very few cancer patients participate in these studies. The purpose of this study was to describe psychosocial barriers to clinical trial participation among oncologists and their cancer patients. A survey was distributed to all medical oncologists in Pennsylvania and a subset of their patients. Relevant background information and assessment of practical and psychosocial barriers to clinical trial participation were assessed. Among 137 oncologists and 170 patients who completed the surveys, 84% of patients were aware of clinical trials, and oncologists and patients generally agreed that clinical trials are important to improving cancer treatment. However, oncologists and patients were more likely to consider clinical trials in advanced or refractory disease. When considering 7 potential barriers to clinical trials, random assignment and fear of receiving a placebo were ranked highly by both patients and oncologists. Patients identified fear of side effects as the greatest barrier to clinical trial participation, whereas oncologists ranked this psychosocial barrier as least important to their patients. Overall, the study found that although oncologists and patients are aware of clinical trials and have favorable attitudes toward them, psychosocial barriers exist for patients that may impact participation in clinical trials. Furthermore, important discrepancies exist between the perceptions of oncologists and those of patients regarding what the psychosocial barriers are. We concluded that characterizing oncologist and patient perceived barriers can help improve communication and decision making about clinical trials, such that participation may be optimized.
影响因子：
45.3
作者：
Meropol, NJ;Weinfurt, KP;Schulman, KA
通讯作者：
Schulman, KA
提高低收入少数族裔妇女子宫颈抹片检查异常后的依从性：预防性电话咨询策略。
DOI：
10.1093/jnci/89.10.703
发表时间：
1997
期刊：
Journal of the National Cancer Institute
影响因子：
--
作者：
Miller,SM;Siejak,KK;Schroeder,CM;Lerman,C;Hernandez,E;Helm,CW
通讯作者：
Helm,CW
医生与患有局限性乳腺癌的老年女性之间的沟通：对治疗和患者满意度的影响。
DOI：
10.1200/jco.2002.20.4.1008
发表时间：
2002
期刊：
Journal of clinical oncology : official journal of the American Society of Clinical Oncology
影响因子：
--
作者：
Liang,Wenchi;Burnett,CarolineB;Rowland,JuliaH;Meropol,NealJ;Eggert,Lynne;Hwang,Yi-Ting;Silliman,RebeccaA;Weeks,JaneC;Mandelblatt,JeanneS
通讯作者：
Mandelblatt,JeanneS