Evaluating Online direct-to-consumer marketing of genetic tests: Informed choices or buyers beware?
Evaluating Online direct-to-consumer marketing of genetic tests: Informed choices or buyers beware?
复制标题
DOI：
10.1089/gte.2007.0024
复制
发表时间：
2008-03-01
期刊：
影响因子：
--
通讯作者：
Einsiedel, Edna
中科院分区：
文献类型：
--
作者：
Geransar, Rose;Einsiedel, Edna
基因技术的商业化正在扩大直接面向消费者的基因检测营销和销售的范围。这项研究评估了信息的提供和访问要求，是在地方的基因检测，是在互联网上的DTC广告。将DTC基因检测的关键词输入流行的互联网搜索引擎，生成24家从事DTC广告的公司名单。公司对医生调解、遗传咨询安排和信息提供的要求被编码，以在每个变量内开发定量分析的类别。结果显示，提供风险评估和诊断测试的公司最有可能要求由临床医生进行测试，并建议医生安排咨询。提供增强测试的公司不太可能需要医生调解服务，更可能提供远程遗传咨询。DTC广告通常提供疾病病因的信息;这在多因素疾病的情况下最常见。大多数公司引用外部来源来支持广告中关于测试临床实用性的声明的有效性;提供风险评估测试的公司最经常引用所有信息来源。缺乏独立专业监督的DTC基因检测广告引发了消费者对这些检测的适当使用和解释的令人不安的问题，并对患者护理标准产生了影响。这些影响进行了讨论的背景下，公共卫生系统。
Commercialization of genetic technologies is expanding the horizons for the marketing and sales of genetic tests direct-to-consumers ( DTCs). This study assesses the information provision and access requirements that are in place for genetic tests that are being advertised DTC over the Internet. Sets of key words specific to DTC genetic testing were entered into popular Internet search engines to generate a list of 24 companies engaging in DTC advertising. Company requirements for physician mediation, genetic counseling arrangements, and information provision were coded to develop categories for quantitative analysis within each variable. Results showed that companies offering risk assessment and diagnostic testing were most likely to require that testing be mediated by a clinician, and to recommend physician-arranged counseling. Companies offering enhancement testing were less likely to require physicianmediation of services and more likely to provide long-distance genetic counseling. DTC advertisements often provided information on disease etiology; this was most common in the case of multifactorial diseases. The majority of companies cited outside sources to support the validity of claims about clinical utility of the tests being advertised; companies offering risk assessment tests most frequently cited all information sources. DTC advertising for genetic tests that lack independent professional oversight raises troubling questions about appropriate use and interpretation of these tests by consumers and carries implications for the standards of patient care. These implications are discussed in the context of a public healthcare system.