Young Adult Psychological Outcome After Puberty Suppression and Gender Reassignment
Young Adult Psychological Outcome After Puberty Suppression and Gender Reassignment
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DOI：
10.1542/peds.2013-2958
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发表时间：
2014-10-01
期刊：
影响因子：
8
通讯作者：
Cohen-Kettenis, Peggy T.
中科院分区：
文献类型：
--
作者：
de Vries, Annelou L. C.;McGuire, Jenifer K.;Cohen-Kettenis, Peggy T.
背景技术背景：近年来，通过促性腺激素释放激素类似物抑制青春期已被接受在临床管理的青少年谁有性别焦虑（GD）。目前的研究是对这种方法有效性的第一次长期纵向评估。（22名变性女性和33名变性男性）在青春期接受过青春期抑制的患者进行了3次评估：在青春期抑制开始之前（平均年龄，13.6岁），当引入跨性别激素时（平均年龄，16.7岁），以及性别重置手术后至少1年（平均年龄，20.7岁）。心理功能（GD，身体形象，全球功能，抑郁，焦虑，情绪和行为问题）和客观（社会和教育/专业功能）和主观（生活质量，生活满意度和幸福感）wellings.RESULTS：性别重新分配后，在年轻的成年人，GD缓解和心理功能稳步提高。幸福感与普通人群中同龄年轻人相似或更好。心理功能的改善与术后主观well-being.CONCLUSIONS：一个多学科团队的心理健康专业人员，医生和外科医生，包括青春期抑制，其次是跨性别激素和性别重置手术的临床协议，提供性别焦虑的青年寻求性别重置从青春期早期，有机会发展成为功能良好的年轻人。儿科2014; 134：696-704
BACKGROUND: In recent years, puberty suppression by means of gonadotropin-releasing hormone analogs has become accepted in clinical management of adolescents who have gender dysphoria (GD). The current study is the first longer-term longitudinal evaluation of the effectiveness of this approach.METHODS: A total of 55 young transgender adults (22 transwomen and 33 transmen) who had received puberty suppression during adolescence were assessed 3 times: before the start of puberty suppression (mean age, 13.6 years), when cross-sex hormones were introduced (mean age, 16.7 years), and at least 1 year after gender reassignment surgery (mean age, 20.7 years). Psychological functioning (GD, body image, global functioning, depression, anxiety, emotional and behavioral problems) and objective (social and educational/professional functioning) and subjective (quality of life, satisfaction with life and happiness) well-being were investigated.RESULTS: After gender reassignment, in young adulthood, the GD was alleviated and psychological functioning had steadily improved. Wellbeing was similar to or better than same-age young adults from the general population. Improvements in psychological functioning were positively correlated with postsurgical subjective well-being.CONCLUSIONS: A clinical protocol of a multidisciplinary team with mental health professionals, physicians, and surgeons, including puberty suppression, followed by cross-sex hormones and gender reassignment surgery, provides gender dysphoric youth who seek gender reassignment from early puberty on, the opportunity to develop into well-functioning young adults. Pediatrics 2014; 134: 696-704