Glycosyl azide -: a novel substrate for enzymatic transglycosylations
Glycosyl azide -: a novel substrate for enzymatic transglycosylations
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DOI：
10.1016/j.tetlet.2005.10.040
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发表时间：
2005-12-12
影响因子：
1.8
通讯作者：
Kren, V
中科院分区：
文献类型：
--
作者：
Fialová, P;Carmona, AT;Kren, V
糖基叠氮化合物是糖苷酶新的有效供体。它们的高水溶性有助于转糖基化，其产率与普通O-糖苷相当或更高。叠氮基完全改变了β-N-乙酰氨基己糖苷酶中的β-GalNAc-酶/β-GleNAc-酶比率（从通常的0.3-1.0到< 0.01），与所有已知的糖苷配基相反。(c)2005爱思唯尔有限公司保留所有权利。
Glycosyl azides are new efficient donors for glycosidases. Their high water solubility facilitates transglycosylations with comparable or better yields than common O-glycosides. The azido group totally changes the beta-GalNAc-ase/beta-GleNAc-ase ratio in beta-N-acetylhexosaminidases (from the usual 0.3-1.0 to < 0.01), contrary to all known aglycons. (c) 2005 Elsevier Ltd. All rights reserved.