c-Phosphonoketenimines, characterization and synthetic application to heterocycles
c-Phosphonoketenimines, characterization and synthetic application to heterocycles
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DOI：
10.1021/jo01314a041
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发表时间：
1980-12
影响因子：
3.6
通讯作者：
J. Motoyoshiya;Akinori Teranishi;R. Mikoshiba;I. Yamamoto;H. Gotoh;J. Enda;Y. Ohshiro;T. Agawa
中科院分区：
文献类型：
--
作者：
J. Motoyoshiya;Akinori Teranishi;R. Mikoshiba;I. Yamamoto;H. Gotoh;J. Enda;Y. Ohshiro;T. Agawa
近年来，多功能杂联烯的合成应用得到了广泛的研究。尽管改性乙烯酮和异氰酸酯的化学得到了广泛的发展，2但乙烯亚胺的用途却很少受到关注。 3 从合成的角度来看，合成带有磷酰基 4 作为可消除取代基的烯酮亚胺是很有意义的。之前我们报道了 5 C-膦酮烯酮亚胺 6 的简便制备，它可以作为一种新型的退火试剂。在本文中，我们报告了对这些反应及其在杂环制备中的合成效用的进一步研究。
In recent years, the synthetic applications of multifunctional heteroallenes1 have been widely investigated. In spite of extensive developments in the chemistry of modified ketenes and isocyanates, 2 little attention has been paid to the uses of ketenimines. 3 From a synthetic point of view it was of interest to synthesize a ketenimine bearing a phosphoryl group4 as an eliminatable substituent. Previously we reported5 a facile preparation of a C-phosphonoketenimine6 which acts as a novel annelation reagent. In this paper we report further investigation of these reactions and their synthetic utility for the prepa-ration of heterocycles.