Post-neurosurgical meningitis due to multidrug-resistant Acinetobacter baumanii treated with intrathecal colistin:: Case report and review of the literature

Post-neurosurgical meningitis due to multidrug-resistant Acinetobacter baumanii treated with intrathecal colistin:: Case report and review of the literature
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DOI:
10.1179/joc.2006.18.5.554
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发表时间:
2006-10-01
影响因子:
1.8
通讯作者:
Al Shimemeri, A.
Al Shimemeri, A.
中科院分区:
医学4区
文献类型:
--
作者:
Al Shirawi, N.;Memish, Z. A.;Al Shimemeri, A.

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鞘内注射粘菌素(多粘菌素E)正在成为治疗神经外科术后多药耐药(MDR)鲍曼不动杆菌引起的脑膜炎的重要选择。我们报告一个28岁的男子谁开发脑膜炎由于MDR A。鲍曼不动杆菌伴脑室外引流患者通过鞘内注射粘菌素3.2 mg(每日一次,经脑室外引流(EVD))治疗4周后痊愈,无任何严重副作用。
Intrathecal colistin (Polymxin E) is becoming an important option for the treatment of post-neurosurgical meningitis caused by multidrug resistant (MDR) Acinetobacter baumannii. We report a case of 28-year-old man who developed meningitis due to MDR A. baumannii associated with an external ventricular drain. The patient was cured using a 4-week course of intrathecal colistin 3.2 mg via external ventricular drain (EVD) daily without any serious side effects.