UK Alcohol Treatment Trial: client-treatment matching effects

UK Alcohol Treatment Trial: client-treatment matching effects
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DOI:
10.1111/j.1360-0443.2007.02060.x
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发表时间:
2008-02-01
期刊:
影响因子:
6
通讯作者:
Williams, Paul
Williams, Paul
中科院分区:
医学1区
文献类型:
--
作者:
Heather, Nick;Copello, Alex;Williams, Paul

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目的测试先验假设有关客户端治疗匹配的酒精问题的治疗,并评估更一般的假设,客户端治疗匹配增加了治疗的整体效果。设计务实,多中心,随机对照试验(英国酒精治疗试验:UKATT),开放随访3个月后进入和盲法随访12个月。五个治疗中心,包括七个治疗点,包括国家卫生服务(NHS),社会服务和联合NHS/非法定设施。治疗动机增强疗法和社会行为和网络疗法。测量匹配的假设进行了测试,通过检查客户属性和治疗类型之间的相互作用,在3个月和12个月的后续使用的百分比天戒酒,饮酒量,每饮酒日和分数的酒精问题问卷和利兹依赖问卷的结果变量。结果-五个匹配的假设都没有得到证实,在任何随访点上的任何结果变量。结论研究结果强烈支持项目匹配在美国达成的结论,客户端的治疗匹配,至少是那种检查,是不可能导致实质性的改善酒精问题的治疗效果。这种失败的可能原因,以支持一般匹配的假设进行了讨论,因为是在英国提供酒精问题的治疗UKATT的研究结果的影响。
Aim To test a priori hypotheses concerning client-treatment matching in the treatment of alcohol problems and to evaluate the more general hypothesis that client-treatment matching adds to the overall effectiveness of treatment. Design Pragmatic, multi-centre, randomized controlled trial (the UK Alcohol Treatment Trial: UKATT) with open follow-up at 3 months after entry and blind follow-up at 12 months. Setting Five treatment centres, comprising seven treatment sites, including National Health Service (NHS), social services and joint NHS/non-statutory facilities. Treatments Motivational enhancement therapy and social behaviour and network therapy. Measurements Matching hypotheses were tested by examining interactions between client attributes and treatment types at both 3 and 12 months follow-up using the outcome variables of percentage days abstinent, drinks per drinking day and scores on the Alcohol Problems Questionnaire and Leeds Dependence Questionnaire. Findings None of five matching hypotheses was confirmed at either follow-up point on any outcome variable. Conclusion The findings strongly support the conclusion reached in Project MATCH in the United States that client-treatment matching, at least of the kind examined, is unlikely to result in substantial improvements to the effectiveness of treatment for alcohol problems. Possible reasons for this failure to support the general matching hypothesis are discussed, as are the implications of UKATT findings for the provision of treatment for alcohol problems in the United Kingdom.