Anatomical and visual outcomes of idiopathic macular hole surgery with internal limiting membrane removal using low-concentration indocyanine green
Anatomical and visual outcomes of idiopathic macular hole surgery with internal limiting membrane removal using low-concentration indocyanine green
复制标题
DOI：
10.1097/01.iae.0000247166.11120.21
复制
发表时间：
2007-04-01
影响因子：
3.3
通讯作者：
Williams, George A.
中科院分区：
文献类型：
--
作者：
Lai, Michael M.;Williams, George A.
目的：报告在特发性黄斑裂孔修复术中使用低浓度吲哚菁绿色（ICG）辅助去除内界膜（ILM）的解剖学、视觉和光学相干断层扫描（OCT）结果。方法：回顾性、干预性、非比较性病例系列，包括57例2、3、或4例特发性黄斑裂孔患者行玻璃体切割术，切除内界膜，并在玻璃体内注入0.125%（1.25mg/mL）ICG。58只眼（98%）通过一次手术实现了黄斑裂孔的解剖闭合。视力从术前平均20/100提高到术后20/60（P < 0.0001）。29只眼（49%）术后视力为20/50或更好。术后视力提高≥ 2行者43眼（73%），0 ~ 2行者13眼（22%），3眼（5%）视力下降。术后OCT显示49只眼（89%）黄斑裂孔闭合，中心凹凹陷正常。结论：在特发性黄斑裂孔手术中，低浓度ICG的短暂应用是一种安全有效的辅助ILM剥离的方法。
Purpose: To report the anatomical, visual, and optical coherence tomography (OCT) results of using a brief application of a low concentration of indocyanine green (ICG) to assist the removal of internal limiting membrane (ILM) during idiopathic macular hole repair.Methods: Retrospective, interventional, noncomparative case series of 59 eyes of 57 patients with stage 2, 3, or 4 idiopathic macular holes who underwent pars plana vitrectomy with removal of ILM assisted by a brief (< 30 seconds) intravitreal application of 0.125% (1.25 mg/mL) ICG.Results: The median follow-up period was 13 months (range, 2-40 months). Anatomical closure of the macular hole was achieved in 58 eyes (98%) with a single surgery. Visual acuity improved from a preoperative mean of 20/100 to 20/60 postoperatively (P < 0.0001). Twenty-nine eyes (49%) had postoperative visual acuity of 20/50 or better. Visual acuity improved by >= 2 lines in 43 eyes (73%) and between 0 and 2 lines in 13 eyes (22%) and decreased in 3 eyes (5%). Postoperative OCT showed closure of macular hole with normal foveal depression in 49 (89%) of 55 eyes.Conclusion: A brief application of ICG at a low concentration appears to provide a safe and effective way of assisting ILM peeling during idiopathic macular hole surgery.