Bone mineral density of the thoracolumbar spine in relation to burst fractures: a quantitative computed tomography study
Bone mineral density of the thoracolumbar spine in relation to burst fractures: a quantitative computed tomography study
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DOI：
10.1007/s00586-006-0148-2
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发表时间：
2006-12-01
影响因子：
2.8
通讯作者：
Xu, Hua-Zi
中科院分区：
文献类型：
--
作者：
Dai, Li-Yang;Wang, Xiang-Yang;Xu, Hua-Zi
胸腰椎爆裂性骨折中最常见的模式涉及上级椎骨终板的失效。胸腰椎爆裂性骨折的生物力学研究很多，但与胸腰椎内部结构相关的生物力学研究很少。本研究的目的是检验胸腰椎骨密度（BMD）分布与该区域应力集中相关的假设，因此支持最常见的爆裂性骨折模式。我们用定量计算机断层扫描（QCT）测量了22例患者第一腰椎三个水平的脊柱BMD。在每个节段，从6个部位和每个椎弓根内的1个部位测定骨小梁室的BMD。因此，每个人在总共20个部位测量小梁密度。椎弓根（部位13和14）的平均QCT BMD最高，而椎弓根附近椎体后部的BMD突然降低。研究结果表明，脊柱应力集中与椎体骨密度的区域变化可能与胸腰椎爆裂性骨折的生物力学机制有关。这一发现可能与胸腰椎爆裂性骨折的损伤机制有关，并具有临床意义。
The most common pattern among thoracolumbar burst fractures involves failure of the superior vertebra end-plate. There have been many biomechanical studies of thoracolumbar burst fractures, but the biomechanics related to the internal architecture of thoracolumbar vertebrae has been rarely documented. The objective of this study was to test the hypotheses that distribution of the bone mineral density (BMD) of the thoracolumbar spine is related to the stress concentration in this region and therefore, supports the pattern of burst fractures that occur most commonly. We measured spinal BMD of the first lumbar vertebra in 22 individuals using quantitative computed tomography (QCT) in three levels. At each level, the BMD for the trabecular compartment was determined from each of six sites and from one site within each pedicle. Thus the trabecular density was measured at a total of 20 sites for each person. The highest average QCT BMD was in the pedicle (sites 13 and 14), whereas the BMD was abruptly decreased at the posterior part of the vertebral body near the pedicles. The results of the study indicate that stress concentration of the spine related to the regional variation in vertebral bone density may be implicated in the biomechanical mechanism underlying thoracolumbar burst fractures. This finding may be correlated with the injury mechanism of thoracolumbar burst fractures and of clinical significance.