THE SECRET LIFE OF THE HAIR FOLLICLE
THE SECRET LIFE OF THE HAIR FOLLICLE
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DOI：
10.1016/0168-9525(92)90350-d
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发表时间：
1992-02-01
影响因子：
11.4
通讯作者：
HARDY, MH
中科院分区：
文献类型：
--
作者：
HARDY, MH
哺乳动物的毛囊是一个有待于更多分子遗传学家发现的宝藏。 一小簇表面上均匀的上皮细胞，与一小簇均匀的间充质细胞相邻，如何产生五六个同心圆柱体，每个圆柱体都由一种独特类型的细胞组成，这些细胞合成自己独特的蛋白质？ 现在有证据表明，几种生长因子，细胞粘附分子和其他分子在这个微小器官的调节中发挥重要作用。
The mammalian hair follicle is a treasure waiting to be discovered by more molecular geneticists. How can a tiny cluster of apparently uniform epithelial cells, adjacent to a tiny cluster of uniform mesenchymal cells, give rise to five or six concentric cylinders, each of which is composed of cells of a distinctive type that synthesize their own distinctive set of proteins? There is now evidence that several growth factors, cell adhesion molecules and other molecules play important roles in the regulation of this minute organ.