Colorectal cancer stage at diagnosis and area socioeconomic characteristics in New Jersey
Colorectal cancer stage at diagnosis and area socioeconomic characteristics in New Jersey
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DOI：
10.1016/j.healthplace.2008.09.003
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发表时间：
2009-06-01
期刊：
影响因子：
4.8
通讯作者：
Roche, Lisa M.
中科院分区：
文献类型：
--
作者：
Henry, Kevin A.;Sherman, Recinda;Roche, Lisa M.
尽管有有效的筛查方法，但研究表明，与生活在富裕地区的人相比，生活在低社会经济地区的人中晚期结直肠癌（CRC）的发病率始终较高。这项基于人群的研究评估了新泽西地区的社会经济指标（ABSM）与结直肠癌诊断分期之间的关系。从新泽西州癌症登记处获得了2000-2005年诊断的50岁及以上的CRC病例。使用logistic回归和空间扫描统计评估地理变异，评估人口普查区域水平ABSM和诊断时CRC分期之间的关联。调整协变量后，包括个人水平的健康保险，ABSM与诊断阶段显着相关。随着地区社会经济条件的恶化，在晚期被诊断的几率增加。虽然增加CRC筛查服务的所有新泽西人口是必要的。这项研究表明，生活在低社会经济水平地区的人可以从加强CRC教育、筛查工作和指导性干预中获益最多。(C)2008爱思唯尔有限公司版权所有。
Despite effective screening methods, research suggests consistently higher rates of late stage colorectal cancer (CRC) among persons living in low socioeconomic areas compared to those living in affluent areas. This population-based study evaluated the association between area-based socioeconomic measures (ABSMs) and CRC stage at diagnosis in New Jersey. Cases of CRC among persons 50 years and older, diagnosed from 2000-2005, were obtained from the New Jersey State Cancer Registry. Associations between census tract-level ABSMs and CRC stage at diagnosis were evaluated using logistic regression and geographic variation assessed using a spatial scan statistic. After adjusting for covariates, including individual-level health insurance, ABSMs were significantly associated with stage at diagnosis. As area socioeconomic conditions worsened, the odds of being diagnosed at a late stage increased. While increasing CRC screening services for all New Jersey populations is warranted. this study suggests that persons living in low socioeconomic areas could benefit the most from enhanced CRC education, screening efforts, and guided interventions. (C) 2008 Elsevier Ltd. All rights reserved.