THE DIFFUSION SENSITIVITY OF FAST STEADY-STATE FREE PRECESSION IMAGING
THE DIFFUSION SENSITIVITY OF FAST STEADY-STATE FREE PRECESSION IMAGING
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DOI：
10.1002/mrm.1910290212
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发表时间：
1993-02-01
影响因子：
3.3
通讯作者：
BUXTON, RB
中科院分区：
文献类型：
--
作者：
BUXTON, RB
具有附加场梯度脉冲的稳态自由旋进（SSFP）成像对水的自扩散和其他运动非常敏感。在由于单个梯度脉冲引起的扩散衰减的早期理论分析中，Wu和Buxton（J.Magn.Reson. 90，243，1990）得出结论，扩散灵敏度将随着较小的翻转角而增加。在本文中，部分分区分析的不同的回波通路有助于信号被用来说明的贡献，刺激回波通路的扩散时间长，作为源的增强扩散灵敏度与低翻转角。在人体模型和大脑中的实验成像研究表明，小翻转角的信号衰减明显更大，
Steady-state free precession (SSFP) imaging with an added field gradient pulse is strongly sensitive to self-diffusion and other motions of water. In an earlier theoretical analysis of diffusion attenuation due to a single gradient pulse Wu and Buxton (J. Magn. Reson. 90, 243, 1990) concluded that the diffusion sensitivity would be increased with smaller flip angles. In this paper a partial partition analysis of the different echo pathways contributing to the signal is used to illustrate the contribution of stimulated echo pathways with long diffusion times as the source of the enhanced diffusion sensitivity with low flip angles. Experimental imaging studies in phantoms and the brain of a human subject demonstrate substantially greater signal attenuation with small flip angles (