Diversity of incarceration patterns among people who inject drugs and the association with incident hepatitis C virus infection.
Diversity of incarceration patterns among people who inject drugs and the association with incident hepatitis C virus infection.
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注射吸毒者监禁模式的多样性以及与丙型肝炎病毒感染事件的关联。
DOI：
10.1016/j.drugpo.2021.103419
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发表时间：
2021
期刊：
影响因子：
--
通讯作者：
Artenie AA
中科院分区：
文献类型：
--
作者：
Artenie AA
背景对于注射吸毒者（PWID）中短期监禁与丙型肝炎病毒（HCV）感染风险之间的关系知之甚少。我们调查了最近监禁持续不到两年的不同模式是否与HCV获得风险在此population.MethodsWe前瞻性PWID在蒙特利尔（2004-2019年）获得HCV感染的风险。在6个月（直到2011年），然后3个月的时间间隔，参与者进行了HCV抗体或RNA检测，并自我报告他们是否在过去的6个月或3个月内被监禁。如果被监禁，他们报告了监禁的环境和时间。我们拟合了三个独立的多变量时间更新的考克斯回归模型，每个模型对应一个监禁测量值：五.监禁时间不足两年的情况（是/否），按环境分层的监禁（地方警察局/省监狱/无）和按监禁时间划分的监禁情况结果709例PWID随访2315.2人年，HCV感染率为9.9/100人年（95%置信区间（CI）：8.7-11.2）]。在随访期间，248名PWID（35.0%）报告了至少一次不到两年的近期监禁事件。总体而言，与在之前6个月或3个月内未经历监禁的PWID相比，PWID获得HCV的可能性高1.56倍（95% CI：1.13，2.17）。我们没有发现统计学上的显着差异，在监禁（似然比检验P = 0.53和0.44，分别）。ConclusionAny recent involvement lasting less than two years，whether of the setting and time in involvement，was associated with a higher risk of HCV acquisition among PWID.调查结果支持需要扩大获得减少伤害的计划，在短期监禁设置，并在平行，优先考虑以公共卫生为导向的替代品，以监禁PWID在可能的情况下。
BackgroundLittle is known about the relationship between short-term incarceration and risk of hepatitis C virus (HCV) infection among people who inject drugs (PWID). We investigated whether varying patterns of recent incarceration lasting less than two years are associated with HCV acquisition risk in this population.MethodsWe followed prospectively PWID at risk of acquiring HCV infection in Montréal (2004–2019). At 6-month (up until 2011), then 3-month intervals, participants were tested for HCV antibodies or RNA, and self-reported whether they have been incarcerated in each of the previous 6 or 3 months. If incarcerated, they reported the setting and time spent in incarceration. We fit three separate multivariable time-updated Cox regression models, one for each measure of incarceration: any incarceration lasting less than two years (yes/no), incarceration stratified by setting (local police station/provincial prison/no) and incarceration stratified by time in incarceration (≤1 week/>1 week and ≤1 month/>1 month and <2 years/no).ResultsAmong 709 PWID followed over 2315.2 person-years, HCV incidence was 9.9/100 person-years (95% confidence interval (CI): 8.7-11.2)]. During follow-up, 248 PWID (35.0%) reported at least one recent incarceration episode of less than two years. Overall, compared to PWID who did not experience incarceration in the prior 6 or 3 months, PWID who did were 1.56 (95% CI: 1.13, 2.17) times more likely to acquire HCV. We found no statistically significant difference in the magnitude of associations across categories of setting and time in incarceration (likelihood ratio testP= 0.53 and 0.44, respectively).ConclusionAny recent incarceration lasting less than two years, regardless of the setting and time in incarceration, was associated with an elevated risk of HCV acquisition among PWID. Findings support the need to expand access to harm-reduction programs in short-term incarceration settings and, in parallel, to prioritise public health-oriented alternatives to incarcerating PWID where possible.
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DOI：
10.1080/09540120802511869
发表时间：
2009-06-01
影响因子：
1.7
作者：
Small, Will;Wood, Evan;Kerr, Thomas
通讯作者：
Kerr, Thomas
丙型肝炎病毒在被监禁或拘留人群中的传播风险
影响因子：
13.5
作者：
E. Gough;M. Kempf;E. Chamot
通讯作者：
E. Chamot
影响因子：
3.8
作者：
Milloy, M. -J.;Wood, Evan;Kerr, Thomas
通讯作者：
Kerr, Thomas
影响因子：
2
作者：
van der Meulen, Emily
通讯作者：
van der Meulen, Emily
影响因子：
7.7
作者：
Langendam, MW;van Haastrecht, HJA;van Ameijden, EJC
通讯作者：
van Ameijden, EJC