STRUCTURE AND STRUCTURE-FUNCTION-RELATIONSHIPS IN GONADOTROPINS

STRUCTURE AND STRUCTURE-FUNCTION-RELATIONSHIPS IN GONADOTROPINS
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DOI:
10.1051/rnd:19880201
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发表时间:
1988-01-01
期刊:
REPRODUCTION NUTRITION DEVELOPMENT
影响因子:
--
通讯作者:
CAMBARNOUS, Y
CAMBARNOUS, Y
中科院分区:
其他
文献类型:
--
作者:
CAMBARNOUS, Y

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垂体促性腺激素(1)和卵泡刺激素(FSH)以及绒毛膜促性腺激素(CG)都是糖蛋白激素,因此是迄今为止已知的具有激素活性的最复杂的分子。由于其结构的复杂性和在性腺功能中的原始作用,促性腺激素的结构-功能关系引起了蛋白质化学家和生殖内分泌学家的极大兴趣。
Pituitary gonadotropins (LH(1) and FSH) as well as chorionic gonadotropins (CG) are glycoprotein hormones and, as such, are the most complex molecules with hormonal activity known so far. Because of their structural complexity and their primordial role in gonadal functions, the structure-function relationships of gonadotropins are of utmost interest for both the protein chemist and the reproductive endocrinologist.