Physiological function and catalytic versatility of bacterial multihaem cytochromes c involved in nitrogen and sulfur cycling.
Physiological function and catalytic versatility of bacterial multihaem cytochromes c involved in nitrogen and sulfur cycling.
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DOI：
10.1042/bst20110713
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发表时间：
2011-12
影响因子：
3.9
通讯作者：
J. Simon;Melanie Kern;B. Hermann;O. Einsle;J. Butt
中科院分区：
文献类型：
--
作者：
J. Simon;Melanie Kern;B. Hermann;O. Einsle;J. Butt
细菌MCCs（multihaem cytochromes c）代表广泛的呼吸电子转移蛋白。此外，它们中的一些转化底物如亚硝酸盐、羟胺、一氧化氮、肼、亚硫酸盐、硫代硫酸盐或过氧化氢。在许多情况下，尽管MCC可以接受各种底物，但在数据库条目中仅将单一功能分配给特定MCC，从而使其成为多功能催化剂，可以在细菌呼吸，解毒和应激防御机制中发挥多种生理作用。本文简要综述了在氮硫循环中起关键催化作用的微囊藻细胞的结构、功能和生物成因。
Bacterial MCCs (multihaem cytochromes c) represent widespread respiratory electron-transfer proteins. In addition, some of them convert substrates such as nitrite, hydroxylamine, nitric oxide, hydrazine, sulfite, thiosulfate or hydrogen peroxide. In many cases, only a single function is assigned to a specific MCC in database entries despite the fact that an MCC may accept various substrates, thus making it a multifunctional catalyst that can play diverse physiological roles in bacterial respiration, detoxification and stress defence mechanisms. The present article briefly reviews the structure, function and biogenesis of selected MCCs that catalyse key reactions in the biogeochemical nitrogen and sulfur cycles.