Increasing trend of diabetes combined with hypertension or hypercholesterolemia: NHANES data analysis 1999-2012.
Increasing trend of diabetes combined with hypertension or hypercholesterolemia: NHANES data analysis 1999-2012.
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DOI：
10.1038/srep36093
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发表时间：
2016-11-02
影响因子：
4.6
通讯作者：
Zhao J
中科院分区：
文献类型：
--
作者：
Song Y;Liu X;Zhu X;Zhao B;Hu B;Sheng X;Chen L;Yu M;Yang T;Zhao J
为了预防心血管终点，必须控制糖尿病、高血压和高胆固醇血症，因为这些风险因素经常合并发生。从1999年至2012年的国家健康和营养检查调查（NHANES）中获得了36，673名受试者中并发糖尿病，高血压和高胆固醇血症的患病率趋势。并发糖尿病、高血压和高胆固醇血症的患病率从1999-2000年的3%增加到2011-2012年的6.3%（P < 0.001）。糖尿病并发高血压或高胆固醇血症的发生率也显著增加，而并发高血压和高胆固醇血症的发生率在研究期间保持稳定。合并糖尿病、高血压、高胆固醇血症的总体药物治疗从1999-2006年的69.8%改善至2007-2012年的82.4%（P = 0.002）。在合并糖尿病的任何组合中，治疗费用覆盖率为79-82.4%，在并发高血压和高胆固醇血症的亚组中为90.7%。一般治疗目标达成率<25%，在有三个联合危险因素的受试者组中，达成率最低，为14.2%。合并糖尿病的两个亚组的治疗目标达成率分别为20.1%（高血压）和17%（高胆固醇血症），无糖尿病组为24.5%。所有组合的成本覆盖率都有所改善，但总体治疗目标实现率较低，尤其是在并发糖尿病的人群中。
In order to prevent cardiovascular endpoints, control of diabetes, hypertension and hypercholesterolemia is a necessity as those risk factors frequently occur in combination. Prevalence trends of concurrent diabetes, hypertension and hypercholesterolemia in 36,673 subjects were obtained from the National Health and Nutrition Examination Survey (NHANES) from 1999–2012. The prevalence of concurrent diabetes, hypertension and hypercholesterolemia increased from 3% in 1999–2000 to 6.3% in 2011–2012 (P < 0.001). The diabetes with concurrent hypertension or hypercholesterolemia incidences also increased significantly, while the occurrence of concurrent hypertension and hypercholesterolemia was stable over the study period. Overall medical drug treatments for concurrent diabetes, hypertension, hypercholesterolemia were improved from 69.8% in 1999–2006, to 82.4% in 2007–2012 (P = 0.002). Treatment cost coverage rates in any combinations with diabetes were 79–82.4% and 90.7% in the subgroup of concurrent hypertension and hypercholesterolemia. General treatment goal achievement rates were <25%, the lowest rate being 14.2% in the subject groups with three combined risk factors. The treatment goal achievement rates in two subgroups with concurrent diabetes were 20.1% (with hypertension) and 17% (with hypercholesterolemia) and 24.5% in the group without diabetes. Cost coverage improved in all combinations, but the general treatment goal achievement rates were low, especially in the groups with concurrent diabetes.
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作者：
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DOI：
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